唑系配体与双过氧钒配合物相互作用的核磁共振研究  

NMR studies on interactions between diperoxovanadate complex and zole-like ligands

作　　者：李国斌 季丹红 刘容华 杨凤仙 于贤勇[1] 李筱芳[1] 陈建 易平贵[1] 

机构地区：[1]湖南科技大学化学化工学院理论化学与分子模拟省部共建教育部重点实验室分子构效关系湖南省普通高等学校重点实验室,湖南湘潭411201

出　　处：《湖南科技大学学报（自然科学版）》2010年第3期89-92,共4页Journal of Hunan University of Science And Technology：Natural Science Edition

基　　金：国家自然科学基金资助项目(20772027;20803020;20971041);湖南教育厅资助项目(09K081;09B032;09C385)

摘　　要：为探讨取代基团和杂环类型对反应平衡的影响,在模拟生理条件下(0.15 mol/LNaCl溶液),应用多核(1H、13C和51V)NMR技术研究双过氧钒配合物NH4[OV(O)2(2picolinamide)].H2O(简写为bpV(picamd),其中picamd为皮考林酰胺)与唑系配体的相互作用,研究表明bpV(picamd)与有机配体有较强的的反应性,其从强到弱的顺序为:咪唑>2-甲基咪唑>吡唑≈3-甲基吡唑,这说明咪唑类配体的配位能力强于吡唑类,咪唑环上2位取代基影响反应,而吡唑环上3位取代基团不影响反应;竞争配位导致一系列新的6配位过氧钒物种[OV(O)22L]-(L=唑系配体)生成.To explore the effects of the substituted groups and heterocyclic types of the ligands on the reaction equilibrium,the interactions between diperoxovanadate complex NH4[OV(O2)2(picolinamide)]·H2O(Abbr.bpV(picamd)) and a series of zole-like ligands in solution were explored using multinuclear(1H,13C,and 51V) magnetic resonance in 0.15 mol/L NaCl ionic medium for mimicking the physiological condition.The reactivity among these orgnic ligands and bpV(picamd) were imidazole > 2-methylimidazole > pyrazole ≈ 3-methyl-pyrazole.The experimental results indicated that the coordinating ability of imidazole-like ligands is stronger than that of pyrazole-like ligands.The substituted groups in 2-position affected the reaction equilibrium for the imidazole-like ligands;However,the 3-substituted pyrazole has almost the same coordinating ability as the pyrazole.The competitive coordination results in the formation of a series of new six-coordinated peroxovanadate species [OV(O2)2L]-(L = zole-like ligands).

关 键 词：咪唑类配体 双过氧钒配合物 相互作用 核磁 共振研究 complex interactions studies 取代基团 反应平衡 吡唑类 配位能力 取代基影响 有机配体 生理条件 竞争配位 甲基咪唑 NMR技术 杂环类 咪唑环 

分 类 号：N[自然科学总论]