急诊心肌梗塞尿激酶静脉溶栓临床观察  

Thrombolytic therapy using urokinase for acute myocardial infarction in emergency deparrment

作　　者：赵晓东[1] 何忠杰[1] 刘波[1] 党伟[1] 张宪[1] 袁晓玲[1] 马俊勋[1] 果应菲[1] 罗北捷[2] 黄党生[2] 

机构地区：[1]解放军总医院第一附属医院急救部 [2]解放军总医院第一附属医院心内科,北京100037

出　　处：《感染．炎症．修复》2006年第3期141-143,共3页Infection Inflammation Repair

摘　　要：目的:评价急性心肌梗塞(AMI)病人实施绿色通道尿激酶(UK)静脉溶栓治疗效果。方法:统计分析我院189例AMI病人尿激酶给药剂量、平均发病至溶栓时间、院内溶栓时间、再通率、死亡率并和国内外公开发表文献比较。结果:采用绿色通道快速诊断和急诊溶栓治疗,使平均急诊溶栓准备时间减至18min,发病至溶栓平均时间2·4h,再通率78·3%,病死率3·17%,优于已发表的同类治疗报道。结论:急诊绿色通道快速静脉溶栓治疗AMI减少了院内溶栓前时间,提高了AMI再通率,是AMI救治成功的关键环节。Objective: To evaluate the effect of intravenous thrombolytic therapy using urokinase (UK) in acute myocardial infarction (AMI). Methods: 189 cases of AMI patients faken care of in the, emergency department, First Hospital Affiliated to the PLA General Hospital during December 2001 to June 2006, were studied. UK dosage, prethrombolytic time, average time of thrombolysis the average reperfusion rate, and overall mortality were analysed. Results: By Green Thorougfare diagnosis and thrombolysis strategy we reduced the prethrombolysis time to 18 min after arrivel in the emergency depqrlmenr, And we reduced the average time of thrombolysis was reduced to 2.4 h after the onsetf AMI. The average reperfusion rate was 78.3, and the total mortality was 3.17. These results were superior to hat of other reports published up to now. Conclusion:“Green thorougfare” can reduce the time toof effective treatment after AUI and might play an imporfant role in acquiring higher reperfusion rate.

关 键 词：急诊溶栓 急性心肌梗塞 尿激酶静脉溶栓 临床观察 静脉溶栓治疗 急诊绿色通道 再通率 溶栓时间 溶栓治疗效果 准备时间 治疗报道 文献比较 统计分析 平均时间 快速诊断 救治成功 给药剂量 发病 病人 死亡率 

分 类 号：R[医药卫生]