超高压超临界流体撞击流方法制备破壁灵芝孢子粉的工艺研究  

Investigation on Preparation of Sporoderm-Broken Ganoderma Lucidum Spores by the Method of Hyper High Pressure Supercritical Fluid Impinging Streams

作　　者：崔宁[1] 潘家祯[1] 王春涛[1] 杨燕勤[1] 王鲁敏[1] 

机构地区：[1]华东理工大学化工机械研究所,上海200237

出　　处：《华东理工大学学报（自然科学版）》2005年第4期504-508,511,共6页Journal of East China University of Science and Technology

基　　金：国家教育部科学技术研究重点项目(02103);上海市科委纳米基金项目(0243nm107)

摘　　要：介绍了超高压超临界撞击流技术制备破壁灵芝孢子粉的方法及基本原理,对制备工艺进行了研究。加载压力、系统加热温度、保压时间及撞击靶距是影响灵芝孢子粉破壁率的因素,通过正交试验及对加热温度和撞击靶距所做的后续试验,确定了采用自行研制开发的试验系统进行灵芝孢子粉破壁的最佳工艺条件是加载压力300MPa,系统加热温度250°C,保压时间1h,撞击靶距10mm。在此工艺条件下,灵芝孢子粉的破壁率为88.48%。This paper investigates the preparation of sporoderm-broken ganoderma lucidum spores by the method of hyper high pressure supercritical fluid impinging streams. The fundamental principles of this method were also introduced. Factors affected the sporoderm-broken ratio include working pressure, heating temperature, holding time and impinging distance. Through the orthogonal experiments and subsequent experiments on heating temperature and impinging distance, the best technical conditions were confirmed as follows： working pressure 300 MPa, heating temperature 250 ℃, holding time 1 h, and impinging distance 10 mm. On these technical conditions,the sporoderm-broken ratio can reach 88.48%.

关 键 词：超高压 撞击流 超临界 灵芝孢子 破壁率 

分 类 号：TQ46[化学工程—制药化工]