脊柱骨髓瘤的诊断及误诊原因分析  

Spinal Myeloma:Diagnosis and Reasons of Misdiagnose

作　　者：刘水连[1] 曾绍林[1] 严宁[1] 

机构地区：[1]上海长海医院影像科,上海200433

出　　处：《生物医学工程学进展》2012年第1期49-52,共4页Progress in Biomedical Engineering

摘　　要：目的探讨视觉模拟疼痛评分(VAS)和止痛剂对于诊断脊柱骨髓瘤的意义。分析脊柱骨髓瘤延误诊断的原因。方法将28例多发性骨髓瘤(MM)病例,按照一定标准选择配对患者组和对照组。统计评分止痛药物的使用情况。结果两组的VAS评分和止痛药物使用情况都有统计学差异。28例患者中,尿本周氏蛋白的假阴性率是46.4%,血清蛋白电泳的假阴性率是21.4%,血沉的假阴性率是3.6%。重视不足是延误诊断的主要原因。结论 VAS评分和止痛药物使用情况在一定意义上可以提示脊柱多发性骨髓瘤。Objective To study the effect of visual analogue pain score(VAS) and analgesic on spinal myeloma diagnosis and the reasons of spinal myeloma delayed diagnosis.Methods Reviewing the clinical data of 28 patients diagnosed multiple myeloma(MM) admitting diagnosis,and laboratory diagnosis.Another 28 patients were chosen as the control group,according to certain selection criteria,matching with the multiple myeloma patients.VAS score and analgesic dosage of both the MM group and the control group were recorded.Comparisons were made between the two groups.Results The VAS scores and analgesic drug have statistical differences between the two groups.Of the 28 patients,the false negative rates were,46.4%,21.4%and 3.6%of urinary Bence-Jones protein,serum protein electrophoresis and ESR,respectively.Insufficient attention and carelessness are the main causes of delayed diagnosis.Conclusion VAS score and analgesic drug are beneficial to diagnosing spinal multiple myeloma.

关 键 词：脊柱 骨髓瘤 诊断 误诊 

分 类 号：R738.1[医药卫生—肿瘤]