病灶刮除骨水泥充填术治疗骨盆四肢转移性骨肿瘤  

Curettage plus cement reconstruction in the treatment of metastatic tumors of pelvis or limbs

作　　者：黄平[1] 董英海[1] 张钟元[1] 马涛[1] 周健[1] 李海蒙[1] 

机构地区：[1]上海第二医科大学附属仁济医院骨科,上海200127

出　　处：《临床骨科杂志》2005年第4期331-333,共3页Journal of Clinical Orthopaedics

摘　　要：目的评价骨水泥病灶充填术治疗骨盆四肢转移性骨肿瘤的疗效和适应证.方法52例骨盆四肢转移性肿瘤患者,34例采用肿瘤刮除加骨水泥病灶充填或加内固定治疗,18例采用植骨或截肢治疗.术后随访生存时间、疼痛改善程度和生存质量.结果随访5～62个月,术后1、2、3年生存率骨水泥组分别为91.2%、82.4%、52.9%,非骨水泥组分别为44.4%、22.2%、11.1%.术后1个月疼痛改善有效率骨水泥组为88.2%,非骨水泥组为33.3%.术后生存质量提高和稳定率骨水泥组为76.5%,非骨水泥组为33.3%.经χ2检验两组差异有显著性(P＜0.05).结论骨水泥病灶充填治疗骨盆四肢转移性骨肿瘤能提高生存时间,改善生活质量.Objective To evaluate the effects and indications of curettage plus cement reconstruction in the treatment of metastatic tumors of pelvis or limbs. Methods 52 patients with metastatic tumors of pelvis or limbs were divided into 2 groups. The bone cement group（34 cases） were treated with curettage plus cement reconstruction, and some of which accepted internal fixation. The control group（ 18 cases） were treated with amputation or curettage plus bone graft. The survival duration, pain improvement and life quality were followed up,postoperatively. Results The postoperative follow-up ranged from 5 to 62 months. The postoperative survival rates at one year, two years, and three years of bone cement group were 91.2% ,82. 4% and 52. 9% , those of the control group were 44. 4% , 22.2% and 11.1% , respectively. In 1 month after operation, the pain was relieved in 30 cases （88.2%） in bone cement group and 18 cases （33.3%） in control group. The life quality improvement and stability rate was 76.5% in bone cement group, and 33.3% in control group. X^2 test showed significant difference between the two groups（P 〈 0. 05）. Conchlsions Curettage plus cement reconstruction is effective in treating metastatic tumors of pelvis or limbs. It can prolong the life expectancy and improve the life qualities.

关 键 词：骨肿瘤/外科学 肿瘤转移 

分 类 号：R738.1[医药卫生—肿瘤]