CT和MRI确定鼻咽癌原发肿瘤靶区的比较  

The Comparion between the Diagnosis Value of CT and of MRI for Delineating Gross Target Volume of Nasopharyngeal Carcinoma

作　　者：胡国清[1] 唐曦[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院肿瘤中心,武汉市430030

出　　处：《中国肿瘤临床》2005年第16期906-909,共4页Chinese Journal of Clinical Oncology

基　　金：国家自然科学基金资助(编号:30470525)

摘　　要：目的:探讨鼻咽癌放疗计划设计中CT和MRI确定肿瘤靶区(GTV)的价值比较。方法:分析经病理证实的39例NPC患者的影像学资料。CT扫描采用GELightspeed型16层螺旋CT机,常规轴位平扫。MRI检查使用GESigna1.5Tesla超导磁共振成像系统。统计方法为配对t检验。结果:MRI组和CT组勾画的靶区中,肿瘤平均体积分别为(32.49±19.91)cm3,(29.06±18.75)cm3,两组对比具有显著性差异(t=5.268,P=0.000)。早期和进展期两组对比有显著性差异(t=5.677,P=0.000;t=3.310,P=0.005)。在T1、T2、T3期中两组对比差异明显(P值分别为0.005、0.001和0.004),而在T4期中两组对比无统计学意义(P=0.146)。结论:MRI组勾画靶区较CT组精确。因此建议在鼻咽癌肿瘤靶区勾画中应以MRI较为适合。Objective： To study the accuracy between CT and MRI in delineating gross tumor volume （GRIN） of nasopharyngeal carcinoma （NPC） when making radiotherapy plan. Methods： Thirty-nine cases with nasopharyngeal carcinoma confirmed by pathology, selected during the period from April 2003 to April 2004, were reviewed retrospectively. CT scanning was performed with GE Light speed 16, routine axial scan was parallel to the OM line from soft palate to the suprasellar cistern. MR scanning was performed by GE Signa super-conducting magnetic resonance imaging system （1.5 Tesla）. All data were analyzed using the paired-samples t test. Results： The mean primary tumor volume （cm3） of CT Group and MR Group were 32.49±19.91 and 29.06±18.75 respectively, and the difference between the two groups was significant （t=5.268, P=0.000）. There were significant differences in the two groups at early stage and advanced stage by Fuzhou Staging System （t=5.677,P=0.000; t=3.310,P=O.O05, respectively）. There was significant difference in Stage T1, T2, T3 （P=0.005, P=0.001, P=0.004, respectively）, but not in stage T4 （P=0.146）. Conclusion： MR is more accurate than CT in delineating GTV of NPC, so it is more valuable in making radiotherapy plan.

关 键 词：鼻咽肿瘤 体层摄影术 X线计算机 磁共振成像 肿瘤靶区 

分 类 号：R739.63[医药卫生—肿瘤]