年轻妇女子宫内膜癌的高危险因素—多囊卵巢  

Polycystic Ovary, the High Risk Factor of Endometrial Carcinoma in Young Woman

作　　者：李秀琴[1] 张淑兰[1] 杜丽敏[1] 陆景明[1] 王育民[1] 

机构地区：[1]中国医科大学附属第二临床学院妇产科,沈阳市110004

出　　处：《中国肿瘤临床》2005年第16期945-947,共3页Chinese Journal of Clinical Oncology

摘　　要：目的:探讨年轻妇女子宫内膜癌与多囊卵巢的关系。方法:对15例患者术前用彩超测量子宫内膜厚度(双层法);术中测量卵巢长、宽径,按“π/6×长×宽2”公式计算两侧卵巢体积;术后常规病理检查。结果:15例中多囊卵巢者11例(73.3%),双侧卵巢体积均明显增大(平均卵巢体积22.94cm3),是非多囊卵巢者的3.55倍;均有明显月经紊乱,其中反复激素治疗8例(72.7%)。而平均子宫内膜厚度为2.35cm,约为正常子宫内膜厚度的2倍左右。结论:多囊卵巢患者自身内源性雌激素增多和治疗过程中外源性雌激素应用所导致的子宫内膜增厚是年轻妇女子宫内膜癌的高危险因素。Objective： To study the relationship between the endometrial carcinoma in young woman and the polycystic ovary, Methods： A total of 15 young women with endometrial carcinoma were included in this study, the thickness of endometrium was measured with ultrasound （double-layer method）; The length and width of ovary were measured, the ovarian volume was calculated with the formula of π/6 × length × width^2; Pathological examinations were performed after operation. Results： Among the 15 cases with endometrial carcinoma, 11 were polycystic ovary （73.3%）, the ovarian volume was increased significantly in both sides （average ovarian volume was 22.94cm^3）, which was 3.55 times bigger than normal ovary; However, the average endometrial thickness was 2.35 cm, which was about 2 times thicker than normal endometrium. All of 11 PCO cases had irregular menstruation, 8 of them had been treated with hormone repeatedly （72.7%）. Conclusions： The increase of endometrial thickness caused by endogenous estrogen and extragenous estrogen in patients with polycystic ovary is the high risk factor for endometrial carcinoma in young woman.

关 键 词：年轻妇女 子宫内膜癌 高危险因素 多囊卵巢 

分 类 号：R737.33[医药卫生—肿瘤]