青少年型帕金森病60例临床分析  

The clinical analysis of 60 patients with juvenile parkinsonism

作　　者：严新翔[1] 郭纪锋[1] 唐北沙[1] 张玉虎[1] 

机构地区：[1]中南大学湘雅医院神经内科,长沙410008

出　　处：《卒中与神经疾病》2005年第4期227-229,共3页Stroke and Nervous Diseases

基　　金：国家863计划项目(2004AA227040);国家科技攻关计划项目(2002BA711A0703);国家自然科学基金项目资助项目(30070273);高等学校博士学科点专项科研基金(20020533024)

摘　　要：目的探讨我国青少年型帕金森病(juvenileparkinsonism,JP)的临床特点。方法对60例JP患者的临床资料进行回顾性分析。结果本组患者中男37例,女23例,发病年龄早,平均发病年龄为(30.1±9.2)岁,病情轻,病程长,病情进展较缓慢,常表现为局限性肌张力障碍,症状波动,腱反射活跃或亢进,CT或MRI检查一般正常,且对多巴制剂反应良好。结论JP患者有其独特的临床特征,临床需与其他疾病相鉴别,以免误诊。Objective To explore the clinical features of juvenile parkinsonism （JP）. Methods The clinical manifestations of 60 patients with JP were analysed retrospectively. Results 60 JP patients were identified,including the male 37 cases and the female 23 cases. Age at onset was young,mean 30. 1 ± 9. 2 years. The symptoms of the parkinsonian triad were mild and slow and the course of the disease was progressive slowly. Gait abnormality,diurnal, fluctuation of sympotoms and hyperreflexia were relatively prominent. Brain CT and MRI were often normal. Response to levodopa was satisfactory. Conclusions The clinical features of patients with JP are peculiar. JP .should be differentiated from other diseases to avoid misdiagnosis.

关 键 词：青少年型帕金森病 临床 诊断 

分 类 号：R742.5[医药卫生—神经病学与精神病学]