羊膜移植与自体角膜缘移植治疗翼状胬肉的初步疗效对照  

Amniotic Membrane Transplantation Versus Limbal Autograft Transplantation For The Treatment Of Pterygium

作　　者：李线 周灵[2] 李绍伟 

机构地区：[1]暨南大学医学院附属第二医院深圳市人民医院眼科,深圳518020 [2]惠州市人民医院眼科 [3]青岛眼科医院

出　　处：《中国实用眼科杂志》2005年第8期857-859,共3页Chinese Journal of Practical Ophthalmology

基　　金：广东省医药卫生科研立项课题(B2002107)基金资助

摘　　要：目的比较评价新鲜羊膜移植与自体角膜缘移植在翼状胬肉治疗中的效果。方法翼状胬肉患者42例48眼。分为羊膜移植组及角膜缘移植组,每组24眼。分别行翼状胬肉切除联合新鲜羊膜移植和自体角膜缘移植。术后随访12～19个月,观察翼状胬肉复发率。结果羊膜移植组6眼(26%)复发,角膜缘移植组3例(13.6%)复发。在初发性胬肉治疗中两组分别有3眼(20%)、2眼(14%)复发;在复发性胬肉治疗中两组分别有3眼(37%)、1眼(12.5%)复发。结论在防止胬肉复发方面,羊膜移植与角膜缘移植在治疗初发性胬肉中疗效相当;角膜缘移植治疗复发性胬肉疗效优于羊膜移植。Objective To evaluate the efficacy of fresh amniotic membrane transplantation compared with limbal autograft transplantation on pterygium treatment. Methods Forty eight eyes of 42 patients with pterygium were divided into two groups, each having 24. They were treated by fresh amniotic membrane transplantation （AMT） and limbal autograft transplantation （LAT） respectively. Recurrent rate was observed during the 12 to 19 follow- up time. Results Six （26%） of 23 eyes, three （ 13.6% ） of 22 eyes showed recurrence after AMT and LAT, respectively. Three of 15 eyes （20%） and two （ 14% ） of 14 eyes showed recurrence after AMT and LAT for primary pterygium, respectively. And Three （37%） of 8 eyes and one （12.5%） of 8 eyes showed recurrence for recurrent pterygium in each group respectively, Conelusions The efficacy of AMT for primary pterygium recurrence is equivalent to that of LAT. LAT may be preferred over AMT for recurrent pterygium.

关 键 词：羊膜移植 角膜缘移植 翼状胬肉 治疗 自体角膜缘移植 翼状胬肉治疗 新鲜羊膜移植 移植治疗 疗效对照 复发性胬肉 

分 类 号：R777.33[医药卫生—眼科] R779.6[医药卫生—临床医学]