黄曲霉毒素生物合成途径调节基因aflR  

The Aflatoxin Biosynthetic Pathway Regulatory Gene

作　　者：陈茹[1] 刘钟滨[1] 

机构地区：[1]同济大学医学院病原生物学教研室,上海200092

出　　处：《细胞生物学杂志》2005年第4期431-434,共4页Chinese Journal of Cell Biology

摘　　要：黄曲霉毒素生物合成途径调节基因在黄曲霉毒素产生过程中发挥十分重要的作用,它为绝大多数黄曲霉毒素合成相关基因的表达所必需。黄曲霉毒素生物合成途径调节基因的启动子中,含有若干真菌转录因子同源物的假定结合位点。AflR蛋白是黄曲霉毒素生物合成途径中的主要正性转录因子,它调节大多数黄曲霉毒素合成相关基因,也包括其自身基因的表达。The aflatoxin biosynthetic pathway regulatory gene plays a key role in the production of aflatoxin, and it is required for the expression of most aflatoxin pathway genes. In the promoter of the aflatoxin biosynthetic pathway regulatory gene, there exist some putative binding sites for homologs of fungal transcription factors. The AflR protein acts as a main positive transcription factor in the aflatoxin biosynthetic pathway, and the AflR protein can modulate the expression of most aflatoxin pathway genes including its own gene.

关 键 词：黄曲霉毒素 黄曲霉毒素生物合成途径调节基因 生物合成 生物合成途径 调节基因 相关基因 转录因子 产生过程 结合位点 启动子 

分 类 号：Q935[生物学—微生物学]