十二指肠溃疡病人血小板活化因子的检测  

DETECTION OF PLASMA PLATELET-ACTIVATING FACTOR IN PATIENTS WITH DUODENAL ULCER

作　　者：倪萍 张成森 刘翠薇[2] 

机构地区：[1]青岛市中心医院急救中心,山东青岛266042 [2]青岛大学医学院附属医院神经外科

出　　处：《齐鲁医学杂志》2005年第4期296-297,300,共3页Medical Journal of Qilu

摘　　要：①目的研究血小板活化因子(PAF)与十二指肠溃疡的相关性.②方法用放射免疫法测定健康对照组和十二指肠溃疡病人血中PAF水平.③结果急性期、恢复期十二指肠溃疡病人血中PAF水平高于同期健康对照组,差异均有统计学意义(t=5.59～19.48,P＜0.05);病人组PAF水平急性期较恢复期高,差异有统计学意义(F=40.33,q=6.96、12.68,P＜0.01).④结论PAF在十二指肠溃疡的发病过程中可能起重要作用.Objective To explore the relationship between plasma platelet-activating factor （PAF） level and duodenal ulMethods Plasma PAF levels in 40 patients and 38 controls were measured by radioimmunodetection.Results The level of PAF in acute and convalescent period were higher than that of the controls （t=5.59-19.48, P〈0. 05）.Plasma PAF levels were higher in acute period than in convalescent period（F=40.33;q=6.96,12.68;P〈0.01）.Conclusion PAF plays an important role in the development of duodenal ulcer.

关 键 词：血小板活化因子 十二指肠溃疡 放射免疫测定 

分 类 号：R574.51[医药卫生—消化系统]