立体定向放射治疗脊柱转移瘤疗效分析  

Analysis on Stereotactic Radiotherapy for Spinal Metastases

作　　者：陈永顺[1] 单国用[1] 庆明轩 张大勇[1] 张现军[1] 

机构地区：[1]郑州市第五人民医院放疗科,河南郑州450003

出　　处：《河南肿瘤学杂志》2005年第5期333-334,共2页Henan Journal of Oncology

摘　　要：目的观察立体定向放射治疗脊柱转移瘤的疗效与不良反应.方法应用全身伽玛刀治疗脊柱转移瘤24例,肿瘤组织照射剂量38.2～46.8 Gy,10～13分次,13～17天完成.结果放疗后疼痛完全缓解(CR)7例,部分缓解(PR)12例,轻微疗效(MR)2例,止痛有效率90.5%.骨转移灶完全消失3例,明显缩小13例,治疗后生活质量评分较治疗前明显改善,消化道反应和骨髓抑制等不良反应轻微.结论立体定向放射治疗脊柱转移瘤止痛效果迅速持久,能明显改善患者的生活质量,控制肿瘤效果满意,值得推广.Objective To evaluate the curative effect and side-effect of stereotactic radiotherapy for spinal metastases. Methods 24 patients with spinal metastases were received stereotactic radiotherapy. The method of radiotherapy was 2.8 - 3.6 Gy per fraction , with a total dose of 38.2 - 46.8 Gy in 10- 13 times over 13 - 17 days. Results The total remission rate of pain was 90.5% （19/21）, all the patients were improved in the quality of life and no evident side-effect was showed. Conclusions Stereotactic radiotherapy should be considered as an effective approach in the treatment of spinal metastases.

关 键 词：立体定向放射治疗 脊柱转移瘤 疗效 

分 类 号：R730.55[医药卫生—肿瘤] R738.1[医药卫生—临床医学]