剥夺睡眠脑电图在局灶性发作诊断中的价值  

Evalue of Sleep-Deprivation Electroencephalography in Diagnosis of Partial Seizures in Children

作　　者：陈连红[1] 庞清忠[1] 陆燕芬[1] 陈丽琴[1] 

机构地区：[1]上海交通大学附属儿童医院,上海200040

出　　处：《实用儿科临床杂志》2005年第9期910-911,共2页Journal of Applied Clinical Pediatrics

摘　　要：目的观察局灶性发作患儿剥夺睡眠脑电图检查的敏感性及其实用价值.方法随机抽取临床有反复发作疑似癫癎,且常规脑电图检查正常患儿102例(男63例,女39例,年龄3～12岁,平均7.3岁).行剥夺睡眠脑电图检查,剥夺睡眠时间＜7岁为18～20 h,＞7岁为24 h.按同样方法检测正常对照组106例(男57例,女49例,年龄3～12岁,平均7.6岁).结果所有病例脑电图的背景电活动频率明显变慢,棘/尖慢复合波等癫癎样放电57例;异常率为55.88%;其中局灶性发作异常率为76.32%,全面性发作异常率为43.8%(χ2=8.98 P＜0.01).对照组诱发后脑电图异常出现癎样放电2例(1.89%),与疑似癫癎组比较(χ2=71.95 P＜0.01),差异非常显著.结论剥夺睡眠后脑电图出现癫癎样电活动的敏感性高于常规脑电图检查,而局灶性发作的敏感性高于全面性发作.Objective To evaluate the sensitivity of sleep- deprivation electroencepbalography（EEG） examination in diagnosis of partial seizures of children. Methods （hae hundred and six normal children （ male 57, female 49. 3 - 12 years old）and 102 children suspected of epilepsy but with normal in standard EEG examination were ~lected at random（male 63, female 39,3 - 12 years old）. Sleep - deprivation EEG was performed individually. Periods of sleep - deprivation were 18 - 20 hours for children below 7 years old and 24 hours for the older ones. Results The EEG showed slowing of background electric activity. In addition, 57 cases showed spindle/ sharp - slow wave complex. The rate of EEG abnormality was 55.88%. The rates of EEG abnormality for partial seizurea and generalized ,seizure were 76.32 % and 43.8%, respectivdy（χ^2 = 8.98 P 〈0.01 ）, while suspected of epilepsy group and normal control group （χ^2= 71.95 P 〈0.01 ）. Conclusion Sleep- deprivation EEG is more ,sensitive than standard EEG, while partial seizures is more sensitive than generalized seizure in showing abnormal electric activity, and it has practical value.

关 键 词：睡眠 剥夺 脑电图 儿童 发作 

分 类 号：R742.1[医药卫生—神经病学与精神病学]