系数倍率法与吸收度减法技术联用测定甲硝唑葡萄糖注射液中5-HMF的含量  

Quantitative Determination of 5-HMF in Metronidazole and Glucose Injection by Combined usage of K-ratio Spectrophotomerty and Absorbance Subtraction Technique

作　　者：黄颂 李枝瑞 

机构地区：[1]宁德市药品检验所,宁德352100 [2]宁德市人民医院,宁德352100

出　　处：《海峡药学》2005年第4期57-58,共2页Strait Pharmaceutical Journal

摘　　要：目的对甲硝唑葡萄糖注射液中5-HMF进行定量。方法应用系数倍率法与吸收度减法技术联用,不经分离在284nm、320nm波长处直接测定。结果消除了甲硝唑的吸收干扰,测得5-HMF在284nm波长处的吸收度。结论方法简单,结果准确。OBJECTIVE To determine the concentrations of 5-HMF in metronidazode and glucose injection. METHODS To perform by combined usage of K-ratio spectrophotomerty and absorbance subtraction technique technique at 284nm and 320nm without separating. RESULTS Presents the absorbace of 5-HMF at 284nm,the interference of metronidazole was eliminated. CONCLUSION The method is simple and accurate.

关 键 词：甲硝唑葡萄糖注射液 5-HMF 系数倍率法 吸收度减法技术 含量测定 

分 类 号：R927.2[医药卫生—药学]