多模式诱发电位对缺氧性脑病的研究  

Multimodal evoked potentials on hypoxic encephalopathy

作　　者：庞英[1] 宿英英[1] 

机构地区：[1]首都医科大学宣武医院神经内科,北京100053

出　　处：《中华神经科杂志》2005年第8期491-494,共4页Chinese Journal of Neurology

基　　金：北京市科委科研基金资助项目(953304003)

摘　　要：目的应用多模式诱发电位评估缺氧性脑病脑功能损伤程度和预测预后的准确性。方法对44例心肺复苏后、低血压和(或)低血氧导致的昏迷患者进行体感诱发电位、脑干听觉诱发电位监测,并根据Judson、Hall、Cant、Haupt标准进行单模式、多模式以及单模式与多模式之间的比较。结果单模式和多模式各分级标准与预后均有显著相关性,级别越高,预后越差。体感诱发电位预测准确性(Judson标准为84.1%)高于脑干听觉诱发电位(Hall标准为79.5%)。多模式诱发电位预测准确性(Cant标准为88.4%)高于单模式诱发电位。结论多模式诱发电位能更好地反映缺氧性脑病的脑功能损伤程度,Cant标准简便易行,预测准确性高,适于临床推广应用。Objective To evaluate the brain function and predict the prognosis of hypoxic encephalopathy with multimodal evoked potentials. Methods Short-latency somatosensory evoked potential （SLSEP） and Brainstem auditory evoked potential（BAEP） were used to monitor 44 coma patients caused by post-cardiopulmonary resuscitation, hypotension and （or） hypoxemia, to compare simple modalities, multimodalities, and simple modalities with muhimodalities according to Judson, Hall, Cant, Haupt standard. Results Simple modal and multimodal grading standards were closely related to the prognosis, the higher the grade, the poorer the prognosis . The accuracy of SLSEP （Judson standard is 84.1% ） was higher than that of BAEP （ Hall standard is 79.5% ） ; and the accuracy of muhimodal evoked potentials （ Cant standard is 88.4% ） was higher than that of the simple modality. Conclusion Multimodal evoked potentials might better indicate the degree of brain function of hypoxic encephalopathy. Cant standard might be easily carried out, which might highly show the accuracy of the prognosis, and suitably to be spread and applied in work.

关 键 词：诱发电位 心肺复苏术 缺氧 脑 预后 体感诱发电位 缺氧性脑病 多模 脑干听觉诱发电位 预测预后 分级标准 

分 类 号：R742.89[医药卫生—神经病学与精神病学]