阈值前病变1型和阈值期早产儿视网膜病变的激光和冷冻治疗  

Photocoagulation and cryotherapy for prethreshold type 1 and threshold disease of retinopathy of prematurity

作　　者：赵培泉[1] 单海冬[1] 程朝晖[1] 黄欣[1] 

机构地区：[1]复旦大学附属眼耳鼻喉科医院眼科

出　　处：《中华眼底病杂志》2005年第5期278-281,共4页Chinese Journal of Ocular Fundus Diseases

摘　　要：目的评价激光和(或)冷冻治疗阈值前病变1型和阈值期早产儿视网膜病变(ROP)的疗效。方法回顾分析2003年1月30日至2005年1月13日期间通过ROP筛查发现并施行视网膜激光和(或)冷冻治疗的阈值前病变1型和阈值期ROP共15例(29只眼),随访比较治疗前后的ROP病变情况,记录任何有关的局部和全身并发症。结果激光和(或)冷冻治疗的29只眼中,19只眼(65.5%)病变完全退化,7只眼(24.1%)残存牵引状视网膜,3只眼(10.3%)进展为视网膜脱离。初次治疗病变即完全退化者12只眼(41.4%),再次治疗后完全退化者7只眼(24.1%)。治疗中2只眼出现一过性角膜混浊,1只眼发生玻璃体积血,1只眼黄斑区误光凝1处。所有病例均未出现全身并发症。结论对阈值前病变1型和阈值期ROP进行及时的激光和(或)冷冻治疗具有比较满意的疗效。Objective To evaluate the prognosis of photocoagulation and （or） cryotherapy for prethreshold type 1 and threshold disease of retinopathy of prematurity （ROP）. Methods The data of 29 eyes of 15 infants who were diagnosed as with prethreshold type 1 or threshold disease of ROP from Jan 30th, 2003 to Jan 13th, 2005 were retrospectively analysed. Pre- and post operative conditions of ROP were compared in the follow up. Any related local and systemic complications were recorded. Results In 29 eyes which had undergone photocoagulation and （or） cryotherapy, ROP regressed completely in 19 （65. 5%）, remained dragged retina was found in 7 （24. 1%）, and retinal detachment was seen in 3 （10.3%）. ROP regressed completely in 12 eyes （41. 4%） after the initial treatment and in 7 eyes （24. 1%） after the secondary treatment. During the treatment, temporary corneal haze was found in 2 eyes, vitreous hemorrhage occurred in 1 eye, and inadvertent photocoagulation at macular area happened in 1 eye. No systemic complications were found in all cases. Conclusion Timely treatment of photocoagulation and （or） cryotherapy for prethreshold type 1 and threshold disease of ROP may lead to famous prognosis.

关 键 词：视网膜病变 早产儿 阈值前病变 激光手术 冷冻疗法 

分 类 号：R774.1[医药卫生—眼科]