4312例冷冻组织切片中甲状腺疾病的诊断分析  

Interoperational diagnosis of thyroid diseases by frozen sections: an analysis of 4312 cases

作　　者：谢成耀[1] 张桂荣 穆洪[3] 徐红 刘楠[1] 洪声明[1] 王恩华[1] 

机构地区：[1]中国医科大学基础医学院病理教研室,沈阳110001 [2]朝阳市中心医院病理科,辽宁朝阳122000 [3]南开大学医学院,天津300000 [4]盘锦市中心医院病理科,辽宁盘锦124000

出　　处：《诊断病理学杂志》2005年第4期294-295,i0014,共3页Chinese Journal of Diagnostic Pathology

摘　　要：目的了解综合医院日常冷冻组织切片诊断中各种疾病的分布及其甲状腺疾病所占的比例和疾病构成。方法统计分析1年内发生在我院的所有冷冻诊断病例,并对其中甲状腺疾病的冷冻诊断与术后石蜡切片诊断进行对比。结果4312例冷冻组织切片中甲状腺疾病823例(19%),乳腺疾病589例居第二位。结节性甲状腺肿514例,是甲状腺疾病中最常见的类型;而乳头状腺癌为甲状腺恶性肿瘤中最常见的类型(47103);桥本病在甲状腺炎中最常见(2135)。结论甲状腺疾病是病理诊断中的主要疾病,其冷冻诊断准确率达98%以上。Objective To explore the distribution of diseases in diagnosis for routine frozen sections in general hospital, and the proportion of thyroid diseases as well as their composition; and to summarize the diagnostic experience for frozen sections with thyroid diseases. Methods All cases with diagnosis of frozen sections during a year were analyzed with statistic methods, and the diagnosis of frozen and paraffin sections of thyroid diseases was compared. Results There were 823 cases with thyroid diseases in 4312 frozen sections （19%） ; for the second common type was mammary disease （589/823）. The most frequent type of thyroid disease was the nodular goiter （514/823） ; the papillary adenocarcinoma is the most frequent type of thyroid carcinoma （47/103） ; and Hashimoto thyroiditis occured most in thyroiditis （21/35）. Conclusion Thyroid disease accounts for the largest part in diagnosis for frozen sections, and its accuracy is more than 98 %.

关 键 词：冷冻组织切片 甲状腺 诊断 

分 类 号：R736.1[医药卫生—肿瘤]