复方木鸡冲剂治疗慢性乙型肝炎的回顾性研究  

The review study of Compound Muji Powder's effects on chronic patients with hepatitis B

作　　者：韩捷[1] 陈海燕[1] 沈培辰[1] 解慧[2] 吴振彪[2] 王维东[1] 冷南[2] 

机构地区：[1]上海市东方医院特诊部,上海201200 [2]第四军医大学西京医院临床免疫科,陕西西安710032

出　　处：《细胞与分子免疫学杂志》2005年第5期631-633,共3页Chinese Journal of Cellular and Molecular Immunology

摘　　要：目的:观察复方木鸡冲剂在慢性乙型肝炎中的疗效。方法:选择28例服用复方木鸡冲剂及护肝药物的慢性乙型肝炎患者作为治疗组,31例仅用护肝药物的患者作为对照组,观察并比较两组治疗前、治疗结束时、治疗结束3月后临床症状改善率、肝功能、血清肝纤维化指标、部分免疫学指标、血常规及超声诊断参数的变化。结果:复方木鸡冲剂可明显改善患者多项检测参数,包括ALT、AST、r-GT、HA、LN、PCⅢ、IgG、r-球蛋白、AFP、血小板、脾厚度和肝光点异常率,部分作用较为持久。结论:复方木鸡冲剂具有保护肝细胞、抑制肝纤维化、降低AFP水平和减轻脾肿大的作用,对慢性乙肝有良好疗效。AIM： To observe the effects of Compound Muji Powder （CMJP） on chronic patients with hepatitis B. METHODS： 28 chronic patients with hepatitis B were chosen as therapy group who took CMJP and general protecting liver medicine, another 31 patients taking general protecting liver medicine only were taken as control group. Clinic symptom, liver function, serum fibrosis items, parts of immunological items, blood routine test and ultrasound alteration were observed before, after and 3 months after ending of treatment and compared between the two groups. RESULTS： Many detecting items including ALT, AST, r-GT, HA, LN, PC Ⅲ, IgG, r-globin, AFP, PLT, thickness of spleen and echogenicity of liver had changed obviously after CMJP application, and parts of these alteration maintained rather long time. CONCLUSION： Since CMJP could play the role of protecting the liver cells, inhibiting liver fibrosis, decreasing AFP level and reducing the enlargement of spleen, it had good curative effects to chronic hepatitis B patients.

关 键 词：复方木鸡冲剂 肝纤维化 慢性乙型肝炎 

分 类 号：R575.5[医药卫生—消化系统]