阻塞性黄疸大鼠肠道细菌移位的实验研究  

The experimental studies of bacterial translocations in intesinal tracts in rats ill with obstructive jaundice

作　　者：刘金彪[1] 邓荔 刘俊[1] 吕坤章[1] 

机构地区：[1]同济医大附属协和医院

出　　处：《洛阳医专学报》1996年第1期3-6,共4页Journal of Luoyang Medical College

基　　金：国家青年科学基金

摘　　要：本研究通过建立阻塞性黄疸的动物模型，观察阻塞性黄疸大鼠肠道细菌移位，旨在探讨阻塞性黄疸患者易感性增高的机制。实验表明，胆管结扎组厌氧菌培养的阳性率为43．75％，假性手术组全部阴性，提示阻塞性黄疸时肠道内微生态平衡紊乱．肠道细菌移位，可能是导致阻塞性黄疸患者感染率增高的原因之一。In order to probe into the increasing mechanism of susceptibility of the patients ill with obstructive jaundice,the bacterial translocations in intestinal tract in rats ill with obstructive jaundice were observed by building animal test models of obstructive jaundice. The results of the animal tests showed that the positive rate of the anaerobic calture in the group of bile duct ligation was 43. 75% and all is negative in the group of sham operation,indicating that it may be one of the reasons leading to the increasing of infection rate of the patients ill with obstructive jaundice that microecosystem is dysequilibrium and bacteria in intestinal tracts are translocation when obstructive jaundice occurs.

关 键 词：阻塞性黄疸 细菌移位 肠道细菌 病理 

分 类 号：R575.02[医药卫生—消化系统]