抑制口腔白色念珠菌感染的实验研究  

Experiment research of white beads in mouth cavity in enzyme inhibition mold infection

作　　者：曲晓娟[1] 孙慎侠[1] 刘铁玉[2] 李振强[1] 梁又德[1] 毕燕妲[1] 

机构地区：[1]大连大学医学院,辽宁大连116622 [2]大连大学附属医院,辽宁大连116023

出　　处：《大连大学学报》2005年第4期82-84,共3页Journal of Dalian University

基　　金：辽宁省教育厅高校科研项目(2023901016)

摘　　要：[目的]筛选对口腔白色念珠菌具有明显拮抗作用的菌株.[方法]通过纸片琼脂扩散法(K-B法)观察各菌株对白色念珠菌的拮抗作用;再利用试管法观察有拮抗作用菌株对白色念珠菌的抑菌效果.[结果]K-B法表明大肠杆菌、甲型链球菌、卡他球菌对白色念珠菌无抑菌作用,表皮葡萄球菌、微球菌有抑菌作用,但抑菌环小;枯草杆菌有明显抑菌作用.试管法表明表皮葡萄球菌和枯草杆菌对白色念珠菌均有生物拮抗作用,其抑菌率分别为98%和90%.[结论]枯草杆菌是白色念珠菌的理想拮抗菌株.[ Objective ] To Selecte the oral antagonistic bacteria on Candida albicans. [ Methods ] The K - B method was used to observe the antagonistic function of the Eschieri coli ,Staphylococcus epidermidis ,Bacillu ssubtills, Bacillus natto, Proteus sp. , Micrococcus sp. , Moraxella catarrhalis, Streptocoecu.epidermidds on candida albicans. The inhibitory effect on candida albicans was observed though test-tube diluting way. [ Results] Fhe results of the K - B method were Ei coli,S, sp. and Moraxellac atarrhalis have no inhibitory effect on candida albicans. Staphylococcus epidermids, Proteus sp. , Micrococcus sp. and Bacillu ssubtilis have that effect. The results of the test-tube methods were Staphylococcus epidermids clearly inhibits candida albicans from growing, and this effect is more evident than Bacillu ssubtilis and Micrococcus. The suppress the germ rates were Staphylococcus epidermids 98% , Bacillu ssubtil 90%. [ Conclusions] The candida albicans is the strongest antagonistic bacteria among tested bacteria.

关 键 词：白色念珠菌 拮抗菌 K-B法 试管法 

分 类 号：R781.54[医药卫生—口腔医学]