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出 处:《中国运动医学杂志》2005年第5期558-561,共4页Chinese Journal of Sports Medicine
摘 要:目的:探讨牛初乳对长时间强化耐力训练后运动员免疫功能抑制的调节作用。方法:将15名国家健将级赛艇男运动员随机分为运动对照组和牛初乳组。两组运动员同时进行30天内容相同的运动训练,训练期间牛初乳组以15g/d的剂量补充牛初乳。训练期前及训练期后分别测定各组运动员的各项免疫指标。结果:强化耐力训练期后,牛初乳组淋巴细胞数量明显增加,并显著高于运动对照组(P<0.001);CD3+T细胞和CD4+/CD8+比值维持在训练前正常水平,但均显著高于对照组(P<0.01);训练期后,牛初乳组血清球蛋白水平显著高于运动对照组(P<0.01),血清白蛋白及A/G比值却明显低于对照组(P<0.05)。强化耐力训练期后,牛初乳组与运动对照组中性粒细胞、巨噬细胞、IgA和IgG均无显著性差异。结论:强化耐力训练期补充牛初乳能有效防止强化耐力训练期后CD4+/CD8+比值的下降、淋巴细胞数量的减少及血清球蛋白含量的降低。提示牛初乳具有良好的维持机体免疫功能自稳态的作用,有助于防止长时间大强度耐力训练后运动员机体免疫功能的下降。Objective The purpose of this study was to examine the effects of 30 - day bovine colostrums supplementation on immune function in elite rowes during prolonged endurance training. Methods 15 male elite rowers were randomly assigned to a control group and a colostrums group. Each athlete underwent endurance training with identical high intensity for 30 days. Bovine colostrums supplements were given orally during the training. Blood samples were taken before and after training for analyzing immune variables. Results Total lymphocyte count increased significantly after 30 - day training in colostrums group and was higher than that in control group, the difference in lymphocyte counts between two groups was significant ( P 〈 0.001 ).The concentration of CD3^+ T cell the levels of the both were within and the ratio of CD^4+/CD8^+ in colostrums group remained unchanged and the normal range. But the levels of these two variables in colostrums group were significantly higher than that in control group (P 〈 0.01). The bovine colostrums supplements increased the level of serum G but decreased concentration of the serum A and the ratio of A/G. The supplementation with bovine colostrums has no effect on leukocyte, monocyte, neutrophil number and the concentration of IgA,IgG. Conclusion These results suggested that the bovine colostrums supplements abolished exercise - induced decline in the ratio of CD4^+/CD8^+ and post - exercise lymphocytopenia. Thus, bovine colostrums could be a potential nutriment to prevent athletes from exercise - induced immunodepression.
关 键 词:牛初乳 赛艇运动员 耐力训练 免疫功能 机体免疫功能 赛艇运动员 训练期间 牛初乳 耐力 强化 A/G比值 细胞数量 蛋白水平
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