颈动脉粥样硬化斑块与血脂和血液流变学相关性的研究  

The relationship between artherosclerotic plaque in carotid artery and blood lipid and hemorheology

作　　者：施有为[1] 殷丽琼[1] 张晓红[1] 付敏敏[1] 娄青[1] 杨静[1] 刘江潮[1] 张君良[1] 

机构地区：[1]合肥市第一人民医院心内科,230061

出　　处：《安徽医学》2005年第6期486-488,共3页Anhui Medical Journal

摘　　要：目的研究颈动脉粥样硬化斑块与血脂和血液流变学的关系。方法152例受试者经颈动脉超声检查,分为斑块组,无斑块组。受试者空腹12小时,清晨抽取肘静脉血,检测项目:血糖、血脂及血液流变学指标。结果两组受试者血脂水平比较可见斑块组患者的TC水平明显高于对照组,差异有显著性(P<0.05),斑块组与对照组相比, 血液流变学指标明显异常。动脉粥样硬化斑块最常见的部位为颈总动脉(CCA)的分叉处。斑块组中高血压患者明显多于对照组,两组患病率差异有显著性(P<0.05)。结论胆固醇增高和血液流变学异常可能对颈动脉粥样斑块的形成起促进作用。Objective To investigate the relationship between artherosclerotic plaque in carotid artery and blood lipid, hemorheology. Methods The ultrasonography was performed in the carotid arteries of all the 152 subjects. The subjects were divided into a plaque group and a nonplaque group by uhrasonography. Hemorrheological index of the two groups were observed. The fasting blood sugar and lipids were detected respectively. Results The level of cholesterol and Hemorrheological index were significantly higher in plaque group than thase in nonplaque group. The plaque was more frequently encountered at the bifurcation of common carotid artery. There were more hypertensive patients in plaque group than in the nonplaque group. Conclusion Hypercholesterolemia and abnormality hemorheology may contribute to the atherosclerotic plaque in carotid artery.

关 键 词：颈动脉 粥样斑块 血脂 血液流变学 颈动脉粥样硬化斑块 血液流变学指标 血脂水平 血液流变学异常 颈动脉超声检查 颈动脉粥样斑块 高血压患者 受试者 对照组 

分 类 号：R363[医药卫生—病理学]