瓜环与喹啉衍生物包结配合行为研究  

Inclusion Complexing Behavior of Cucurbit[n] urils with Some Quinoline Derivatives

作　　者：牟兰[1] 薛赛凤[1] 祝黔江[1] 陶朱[1] 曾晞[1] 

机构地区：[1]贵州大学应用化学研究所,贵阳550025

出　　处：《高等学校化学学报》2005年第10期1835-1839,共5页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金(批准号:20261002);贵州省科技厅人才培养基金(批准号:20020204);贵州省省长基金;贵州省重点科研项目(批准号:20023004);科技部国际合作项目(批准号:200211003)资助.

摘　　要：利用1H NMR以及荧光技术研究了六、七、八元瓜环与2-苯基喹啉、N-正丙基溴化异喹啉、3-氨基喹啉及7,8-苯并喹啉的相互作用.两种方法的考察结果均表明,2-苯基喹啉能与这3种瓜环发生相互作用,其中六、七元瓜环与2-苯基喹啉形成1∶1的稳定包结配合物,包结常数分别为1.6×104和3.2×103L/mol.八元瓜环能与2-苯基喹啉形成1∶2包结物.1H NMR结果还表明,3种瓜环均能与N-正丙基溴化异喹啉相互作用,其化学计量比均为1∶2;七元瓜环与7,8-苯并喹啉相互作用,化学计量比约为1∶1.荧光法也表明八元瓜环能与N-正丙基溴化异喹啉、3-氨基喹啉及7,8-苯并喹啉发生相互作用,并且荧光强度随瓜环浓度增加而下降,其化学计量比为1∶2.同时,讨论了上述主客体包结配合物的作用模式.The interaction of cucurbit [ n = 6,7,8 ] urils （ Q [ 6 ], Q [ 7 ], Q [ 8 ] ） with some quinoline derivatives, such as 2-phenylquinoline, N-propylquinoline, 3-aminoquinoline and 7,8-phenylquinoline, were studied by using ^1H NMR technique and fluorometric analysis. The experimental results of both methods reveal that 2-phenylquinoline can form stable inclusion complex with Q[6], Q[7 ], Q[ 8] with a ratio of 1： 1, 1：1 and 2：1 respectively, and the inclusion constants of 2-phenylquinoline-Q[ 6 ] or Q[ 7 ] was 1.6 × 10^4 and 3.2 × 10^3 L/mol respectively. ^1H NMR results also show that Q[6], Q[7], Q[8] could form inclusion complex with N-propylquinoline with a ratio of 2：1 repectively, and Q[ 7 ] could form inclusion complex with 7,8-phenylquinoline with a ratio of 1： 1. Fluorometric analysis reveal that the host-guest complexes of Q [ 8 ] and the title quinoline derivatives were formed with a ratio of 1 ： 2 repectively, and the fluorescence of the interacted quinoline derivatives was queched by Q[ 8 ]. Also the interaction models were suggested for the above housguest inclusion complexes.

关 键 词：瓜环 喹啉衍生物 包结配合 ^1H NMR技术 荧光光谱分析 

分 类 号：O621.15[理学—有机化学]