甲醛合次硫酸氢钠氧化反应速率常数的测定  

Determination of the constant of oxidation rate of sodium formaldehyde sulfoxylate

作　　者：曹呈勇[1] 卿荣[1] 史炎[1] 詹先成[1] 舒晓明[1] 李成容[1] 李琳丽[1] 何宁[1] 

机构地区：[1]四川大学华西药学院,四川成都610041

出　　处：《华西药学杂志》2005年第5期399-400,共2页West China Journal of Pharmaceutical Sciences

基　　金：国家自然科学基金(No.30472104)

摘　　要：目的测定甲醛合次硫酸氢钠在水溶液中与氧反应的反应速率常数。方法在不断通入空气的情况下,采用碘量法测定甲醛合次硫酸氢钠在水溶液中不同时刻的浓度,作出降解曲线,并计算反应速率常数。结果甲醛合次硫酸氢钠在溶液中为假一级反应,在碱性、中性和弱酸性条件下反应速率常数分别为5.185×10-4h-1、4.404×10-4h-1和4.909×10-3h-1。结论甲醛合次硫酸氢钠在弱酸性条件下抗氧能力较强,在中性和弱碱性条件下较弱。OBJECTIVE To determine the constants of oxidation reaction rate between sodium formaldehyde sulfoxylate and oxygen in apueous solutions. METHODS Residual concentrations of sodium formaldehyde sulfoxylate in the solutions determined by iodimetry were with linear regressions to obtain the constants of reacting rate. RESULTS The degradation of sodium formaldehyde sulfoxylate obeies the pseudo - first - order kinetics in neutral, weak alkaline and weak acid conditions, and the constants （ k ） were 5.185 × 10^-4 h^-1, 4.404 ×10^-4 h^-1 and 4.909 × 10^-3 h^-1 respectively. CONCLUSION The sodium formaldehyde sulfoxylate to possesses stronger antioxidant activity in weak acid solution than in neutral and alkaline ones.

关 键 词：甲醛合次硫酸氢钠 抗氧剂 氧化反应速率常数 反应速率常数 

分 类 号：R913[医药卫生—药学]