小肝癌DNA含量分析  

DNA content analysis of small hepatocellular carcinoma

作　　者：赵文和[1] 冯懿正[1] 丁伟[1] 周水云[1] 

机构地区：[1]浙江医科大学附属第一医院肿瘤科,浙江医科大学附属第一医院病理科,浙江医科大学形态中心

出　　处：《实用肿瘤杂志》1996年第3期110-112,共3页Journal of Practical Oncology

摘　　要：应用ＭＩＰＳ－１型自动图像分析仪，检测２５例小肝癌标本，探讨肿瘤细胞膜ＤＮＡ含量与小肝癌临床病理学关系。结果表明：肝癌细胞核ＤＮＡ含量与术前ＡＦＰ水平。肿瘤大小、有否包膜形成、ｋａｎａｉ＇分型无关：在肿瘤细胞分化未成熟及复发组病例。ＤＮＡ含量明显增高，提出核ＤＮＡ含量是反映肿瘤细胞生物学恶性程度的重要指标，可望成为独立的预后因子。DNA contents were measured by image analysis technique 25 cases of small hepatocellular carcinome. The results showed that serum AFP levels, tumor size, encapsulation, Kanai's gross type were not related to DNA contents. But DNA contents of low histological grade and recurrent cases were significantly higher than that of its opposition.The author suggested that DNA contents of liver cancer might be an important parameter reflecting bioloical features and clinical prognosis of liver cancer.

关 键 词：DNA 图像分析 小肝癌 肝肿瘤 

分 类 号：R735.7[医药卫生—肿瘤]