感觉根入髓区血管压迫是三叉神经痛的主要病因  

VASCULAR COMPRESSION TO ROOT ENTRY ZONE OF SENSORY ROOT IS THE MAIN CAUSE OF TRIGEMINAL NEURALGIA

作　　者：朱宏伟[1] 李勇杰[1] 胡永生[1] 马凯[1] 

机构地区：[1]首都医科大学宣武医院北京功能神经外科研究所,北京100053

出　　处：《中国疼痛医学杂志》2005年第4期202-203,共2页Chinese Journal of Pain Medicine

基　　金：北京市科技新星计划项目(No.2003B35);北京市卫生局科研项目(No.280)资助

摘　　要：目的:研究显微血管减压手术(microvasculardecompression,MVD)治疗三叉神经痛(trigemi-nalneuralgia,TN)的适应症、术中所见、术后疗效和安全性。探讨TN的主要病因及发病机制。方法:2000年12月到2003年10月间,169例TN患者接受了显微外科手术,手术前后进行了直观模拟量表(VisualAnalogueScales,VAS)评分。结果:术后1周疼痛消失131例,疼痛减轻35例,疼痛无变化3例。手术前后VAS评分分别为8.86±1.08和0.48±0.12,统计结果表明手术前后疼痛改变有显著性差异。术后无死亡病例,手术并发症多为暂时性并发症。随访期间有4例复发。结论:MVD手术的有效性证明了三叉神经感觉根入髓区血管压迫是TN的主要病因。Objective ： To investigate the indications, operative findings, results and safety of microvascular decompression（MVD） for trigeminal neuralgia（TN）） and to explore the etiology and mechanism of TN. Methods： 169 patients with TN were accepted for microsurgical operation. Visual Analogue Scales （VAS） of pain was carried before and after operation. Patients were followed up with telephones or letters. Results： Pain was terminated in 131 cases, relieved in 35 cases, and retained in 3 cases. Statistical results showed there was significant difference in VAS before and after operation. Some patients had transient complications. Four patients experienced recurrence of pain during the following-up periods. Conclusion ： The main cause of TN is the vascular compression of the root entry zone of nerve sensory root trigeminal.

关 键 词：三叉神经痛 显微血管减压手术 病因 血管压迫 微血管减压手术 三叉神经感觉根 VAS评分 手术并发症 术后疗效 显微外科手术 

分 类 号：R745.11[医药卫生—神经病学与精神病学] R651.3[医药卫生—临床医学]