脑苷激肽合并抗精神病药物治疗精神分裂症临床疗效观察  

Study on Effect of Combining Cattle Encephalon Glycoside and Lgnotin Injection with Antimental Disorder Medication for Schizophrenia

作　　者：石洲宝[1] 陈林庆[1] 吴丽荣 孙宏[1] 李红[1] 彭晓明[1] 郭霞[1] 张瑜[1] 

机构地区：[1]甘肃中医学院附属医院神经心理科,730020 [2]兰州市第三医院

出　　处：《神经疾病与精神卫生》2005年第4期275-277,共3页Journal of Neuroscience and Mental Health

摘　　要：目的观察脑苷激肽合并抗精神病药物治疗精神分裂症的临床疗效观察。方法将80例精神分裂症患者随机分为两组,分别给予抗精神病药物合并脑苷激肽联合治疗(观察组),和单用抗精神病药物(对照组),治疗为8周。采用简表精神科量表(BPRS),阴性症状量表(SANS)定期进行评定。结果观察组总有效率为85%,对照组为70%,差异显著(χ2=3.66,P<0.05),两组(BPRS),(SANS)评分在第2周、第4周、第8周、差异均有显著性(P<0.01)。结论用脑苷激肽合并抗精神病药物治疗精神分裂症比单纯应用抗精神病药物疗效显著。Objective To observe the effect of combining cattle encephalon glycoside and lgnotin injection with antimental disorder medicine for treating schizophrenia. Methods 80 patients with schizophrenia were divided randomly into two groups. Experimental group was given antimental disorder medicine with cattle encephalon glycoside and lgnotin Injection and control group was given antimental disorder medicine. The treatment had lasted for 8 weeks. During therapy time, brief psychiatric rating scale （BPRS） and SANS were adopted for evaluation. Results Efficiency rate of experimental group was 85% and that of control group was 72.5%. The difference is remarkable （X^2=3.66, P 〈 0.0 5）. There were significant differences between two groups in the score of BPRS and SANS at second, third, eighth week of treatment （P 〈 0.01）. Conclusions In treating schizophrenia, using cattle encephalon glycoside and lgnotin injection with antimental disorder medicine can get better effect than using antimental disorder medicine only.

关 键 词：精神分裂症 脑苷肌肽 病例对照研究 

分 类 号：R749.3[医药卫生—神经病学与精神病学]