胸部Askin瘤(附2例报告)  

Askin tumor in chest

作　　者：陈景开[1] 陈满清[1] 赵秋良[1] 周辽军[1] 徐燕[1] 夏阳[1] 宗刚军[1] 

机构地区：[1]解放军第101医院呼吸科,江苏无锡214044

出　　处：《东南国防医药》2005年第5期327-331,共5页Military Medical Journal of Southeast China

摘　　要：目的探讨A sk in瘤的临床特征。方法根据收治的2例病例结合文献复习,对本病的起源和本质、病理特征、临床表现、诊断和鉴别诊断、治疗和预后进行系统地阐述。结果A sk in瘤起源于原始神经外胚叶。肿瘤细胞小圆形,核大胞浆少,呈梁状或巢状分布。临床表现无特征性。确诊有赖于组织学和免疫组织化学检查。对放疗和化疗均敏感,但主张综合治疗。本病恶性程度高,转移早而广泛,预后差。结论A sk in瘤是一种发生于儿童和青少年胸肺部少见的原始神经外胚叶小圆细胞肿瘤,恶性程度极高,临床上应加以重视。Objective To investigate the clinical characteristics of Askin tumor. Methods According to references and two cases whose diagnosis were established by biopsy, the origination and nature, characteristics of pathology, clinical manifestations, diagnosis and differential diagnosis, treatment and prognosis of Askin tumor were discussed. Results Askin tumor was origined from neuroectoderm. The tumor cells were roundlet with relatively a few cytoplasm and large cellular nucleus which origin from neuroectoderm. There was no feature in clinical manifestations. The definite diagnosis depended upon the pathology and immunohistochemistry of the tumor. Comprehensive therapy were recommended although chemotherapy and radiotherapy were alternatively effective. Conclusion Askin tumor is one of suffering from chest easily in children and the youth, the tumor is extremely malignant because of its earlier, more extensive metastasis.

关 键 词：恶性肿瘤 小圆细胞 胸部 

分 类 号：R734.4[医药卫生—肿瘤] R730.264[医药卫生—临床医学]