羧甲基壳聚糖对5株口腔颌面部感染细菌的抑菌性能的评价  

Study on the inhibiting bacteria carboxy-methylchitom

作　　者：张永军 高继红[2] 薛毅[3] 苏金波 

机构地区：[1]解放军第266医院口腔科,河北承德067000 [2]承德医学院微生物教研室,河北承德067000 [3]白求恩国际和平医院,河北石家庄050082

出　　处：《中国微生态学杂志》2005年第5期348-348,共1页Chinese Journal of Microecology

摘　　要：目的研究羧甲基壳聚糖对5株口腔颌面部感染细菌的抑菌性能,为在临床应用提供相关资料。方法采用液体梯度稀释法分别测定羧甲基壳聚糖对牙龈卟啉菌、中间普氏菌、金黄色葡萄球菌、大肠埃希菌和铜绿假单胞菌的最低抑菌浓度(M IC)。结果羧甲基壳聚糖对5株菌的M IC分别为:20、5、2.5、5、10 g/L。结论羧甲基壳聚糖对口腔颌面部感染重要相关细菌具有抑菌作用。Objective To study the bacteriostatic efficiency of carboxy-methylchitom. Methods Five strains of oral bacteria （Prophyromonas gingivalis ATCC 33277,Prevotella intemedicus ATCC 25261 ,Staphylococcus aureus,Escherichia coli,Pseudomonas aeruginosa） was selected as the objective, mininum inhibitory concentration（MIC） was measured respectively. Results MIC of five strain of oral bacteria was 20,5,2. 5,5,10 g/L respectively. Conclusion Carboxy-methylchiton had inhibiting bacteria of oral bacteria.

关 键 词：羧甲基壳聚糖 抑菌性 最低抑菌浓度 

分 类 号：R722.6[医药卫生—儿科]