磁共振弥散加权成像与肝硬化程度相关性的研究  

Study of MR diffusion weighted imaging in evaluating the severity of hepatic cirrhosis

作　　者：胡奕[1] 富西湖[1] 郭启勇[1] 陈丽英[1] 

机构地区：[1]中国医科大学附属第二医院放射科,辽宁沈阳110004

出　　处：《中国临床医学影像杂志》2005年第10期564-567,共4页Journal of China Clinic Medical Imaging

基　　金：辽宁省科学技术计划项目(2003225002)

摘　　要：目的:通过磁共振弥散加权成像(MR-DWI)与肝硬化程度的相关性研究,探讨其在评价肝硬化程度方面的价值。材料与方法:对19例正常肝脏及36例不同程度硬化肝脏行MR-DWI,计测并比较表观弥散系数(ADC)值。结果:正常肝脏ADC值(单位:×10-3mm2/s)与硬化肝脏之间有显著差异,分别为2.01±0.20和1.56±0.24(P<0.05);随肝硬化程度进展,ADC值下降,ChildA、B、C级依次为1.76±0.20、1.58±0.13和1.33±0.17,三者之间也有显著差异(P均小于0.05)。结论:MR-DWI与肝硬化程度相关,可望成为评价肝硬化程度的方法。Objective： To find the relation between MR diffusion weighted imaging（MR-DWI） and severity of hepatic cirrhosis, and study the value of MR-DWI in evaluating the severity of hepatic cirrhosis. Materials and Methods： DWI were performed on 55 persons, including 19 normal people and 36 cirrhotic patients with different severities. And then the values of apparent diffusion coefficients（ADCs） were calculated and compared. Results： ADC values of normal livers were higher than those of cirrhotic livers. They were 2.01±0.20 and 1.56±0.24 respectively, there was significant difference between them （P〈 0.05）. With the development of hepatic cirrhosis, ADC values decreased. They were 1.76±0.20, 1.58±0.13 and 1.33±0.17 for Child A, B, C respectively, and significant differences were found among them（P〈0.05）. Conclusion： MR-DWI is relevant to the severity of hepatic cirrhosis, and may be a useful tool for evaluating the severity of hepatic cirrhosis.

关 键 词：肝硬化 磁共振成像 弥散 

分 类 号：R575.2[医药卫生—消化系统] R445.2[医药卫生—内科学]