双探头^(18)F-FDG显像对原发不明转移瘤的诊断价值  

Diagnostic value of dual-head ^(18)F-FDG imaging in metastatic lesion with unknown primary tumour

作　　者：潘衍基[1] 卫光宇[1] 冯彦林[2] 余丰文[2] 刘德军[2] 张宁[1] 

机构地区：[1]佛山市第一人民医院放疗科,528041 [2]佛山市第一人民医院核医学科,528041

出　　处：《中华肿瘤杂志》2005年第9期565-566,共2页Chinese Journal of Oncology

摘　　要：目的探讨双探头18F-FDG显像对原发不明转移瘤(UPT)的诊断价值。方法应用双探头18F-FDG显像检查70例UPT患者,并根据FDG浓聚诊断原发灶。结果根据FDG显像阳性诊断为原发灶58例,其中肺癌42例,全部患者均经病理证实。原发灶诊断符合率为82.9%,以肺癌最常见。FDG显像阴性12例(17.1%),进一步检查诊断原发灶5例,随访中诊断原发灶1例,未能诊断原发灶6例。结论双探头18F-FDG显像诊断UPT原发灶是一种简便、快速、无创、灵敏的方法。原发灶以肺癌最常见。FDG显像原发灶诊断符合率达80%以上,可作为UPT的首选诊断方法。Objective To investigate the diagnostic value of dual-head ^18 F-fluorodeoxyglucose （ ^18 F- FDG） imaging in metastatic lesion with unknown primary turnout （ UPT）. Methods Seventy patients with UPT underwent dual-head ^18F-FDG imaging after iv ^18SF-FDG 1. 85 MBq/kg. The primary turnout was diagnosed according to the FDG uptake and T/N value. Results Of the 70 patients, the primary turnout was identified by positive FDG imaging and finally confirmed pathologically in 58 patients （82.9%） , and 12 patients had a negative FDG imaging （ 17. 1% ）. Forty-two of the 58 positive patients were found to have lung cancer （72.4%）. Among the 12 negative patients, their primary turnout was then identified by other diagnostic procedures in 5 patients （41.7%） , in 1 patlent,the primary, site was detected during follow-up, however, the primary tumour was never detected in the rest 6 patients. Conclusion Dual-probe ^18SF-FDG imaging is a simple, quick, non-invasive and sensitive technique with an accuracy over 80% in the diagnosis of unknown primary turnout. The lung is found to be the most frequent primary site. Dual-probe ^18F-FDG imaging can be recommended as the first diagnostie choice for UPT.

关 键 词：双探头^18F-FDG显像诊断 肿瘤转移 肺肿瘤 ^18F-FDG显像 诊断价值 原发灶 双探头 转移瘤 不明 诊断符合率 

分 类 号：R730.4[医药卫生—肿瘤]