慢性顽固性Beh et病手术治疗的初步观察  

Preliminary observation of the therapeutic effects of vitrectomy on chronic and refractory Beh et′s disease

作　　者：易长贤[1] 郭梦翔[1] 闫宏[1] 潘晓燕[1] 邓燕[1] 

机构地区：[1]中山大学中山眼科中心,广州510060

出　　处：《中华眼底病杂志》2005年第6期357-359,共3页Chinese Journal of Ocular Fundus Diseases

摘　　要：目的观察玻璃体切割手术治疗慢性顽固性Beh et病的疗效。方法回顾分析8例Beh et病患者10只患眼常规玻璃体切割手术治疗后随访观察半年至3年的临床资料,分析手术前后视力、手术后炎症控制以及复发情况。全部患者为双眼发病,5例为完全型、3例为不完全型Beh et病。结果手术中发现患眼均有明显的玻璃体混浊、液化,普遍的视网膜颜色灰暗和视网膜血管变细,部分血管闭塞或伴有不同程度的血管鞘样改变。手术后所有接受治疗眼均有不同程度的视力提高,手术后第1、2周,1、6个月的视力与手术前相比其差异有统计学意义。随访观察期中,1个月内有3只眼出现过炎症复发;6个月内有6只眼出现过炎症复发;4只眼手术后炎症一直未再发。全部患眼均未出现因手术而诱发的急性炎症复发。结论玻璃体切割手术治疗慢性顽固性Beh et病可以提高患眼视力,手术安全有效。Objective To evaluate the therapeutic effects of vitrectomy on chronic and refractory Behcet＇s diseases. Methods The clinical data of 8 patients （10 eyes） with Behcet＇s diseases from 0.5 to 3 years after vitrectomy were retrospectively analyzed. Pre and post-operative visual acuity, control of inflammation after the surgery, and the recurrence were observed and analyzed. Both of the eyes were involved in all of the patients, including complete Behcet＇s diseases in 5 and incomplete in 3. Results Vitreous opacity and liquefaction were found in all of the involved eyes, dark retina and thin retinal vessels were seen in most of the eyes, and vascular obstruction or sheath like changes in different degrees were detected in some eyes. Improvement of visual acuity was observed in all of the eyes which had undergone the treatment after the operation. There was significant difference between the visual acuity before the surgery and at the 1st and 2nd week and the 1st and 6th month after the surgery. During the follow up period, recurrence of the inflammation was found in 3 eyes within 1 month and in 6 eyes within 6 months; no recurrence was found in 4eyesafter the operation. No acute recurrence of inflammation was found after operation in the involved eyes. Conclusion Vitrectomy for chronic and refractory Behcet＇s diseases may improve the visual acuity of the involved eyes, and the surgery is safe and effective.

关 键 词：Behcet病/外科学 玻璃体切除术 玻璃体/病理生理学 视网膜炎 双眼视力 

分 类 号：R779.6[医药卫生—眼科]