葛根素对脑梗死患者血液流变学的影响  

Effects of Puerarin on Blood Rheology of Patients with Cerebral Infarction

作　　者：吴海琴[1] 孙启岗 展淑琴[1] 徐静 袁海峰[1] 甄长安[1] 

机构地区：[1]西安交通大学第二医院神经内科,陕西西安710004 [2]陕西省富平县人民医院内科,陕西富平711700

出　　处：《中国血液流变学杂志》2005年第2期244-246,共3页Chinese Journal of Hemorheology

基　　金：陕西省科技攻关项目(2002K10-G2)。

摘　　要：目的了解葛根素对脑梗死患者血液流变学的影响。方法对56例脑梗死患者进行葛根素治疗,药物用量为0.5加入250mL液体中静脉点滴,每日1次,共治疗14d。采用北京普利生LBY-N5A锥板式血液流变学测定仪对治疗前后血液流变学各指标进行观察、比色法测定血纤维蛋白原含量。同时选取查体健康者38名进行对照研究。结果脑梗死患者存在血液流变学指标异常和血纤维蛋白原增高,葛根素治疗后血液流变学各指标有显著性改善和纤维蛋白原降低。结论血液流变学指标异常和血液纤维蛋白原增高是急性脑梗死的重要危险因素,葛根素对脑梗死患者血液流变学和纤维蛋白原有改善作用,其疗效可靠,值得推广。Objective In order to know effects of puerarin on hemorheology of patients with cerebral infarction. Methods The 56 patients with cerebral infarction were treated with 0.5 gram puerarin a day for 14 days. The change of hemorheology have been observed in patients before and after treatment and in 38 controls. Results The patients were abnormality in hemorheology and increase of fibrinogen. The abnormal hemorheology had significant improved,and coexisted decrease of fibrinogen after treatment. Conclusions The abnormal hemorheology and increased fibrinogen are important risk factors for acute cerebral infarction. The puerarin can improve the abnormal hemorheoloay and decrease fibrinogen.which is available in the treatment of cerebral infarction.

关 键 词：脑梗死 血液流变学 葛根素 

分 类 号：R743.3[医药卫生—神经病学与精神病学]