血管全埋入式药物灌注装置及腹腔区域灌注化疗在进展期胃癌术后抗复发治疗的应用  

Effective of Combined Chemothemotherapy by Embedding of Drug Delivery System (EDDS) and Abdominal Cavity Drug Delivering for the Radical Gastrectomy Patients with Advanced Gastric Cancer (AGC)

作　　者：陆力[1] 杨树鹏 徐长胜 陈兴让 赵璋利 陆振玉[3] 

机构地区：[1]苏州市立医院肿瘤外科,江苏苏州215008 [2]榆林靖边中医院普外科,陕西榆林718500 [3]苏州大学附属第一医院消化内科,江苏苏州215006

出　　处：《中国血液流变学杂志》2005年第2期282-284,共3页Chinese Journal of Hemorheology

摘　　要：目的探讨血管全埋入式药物灌注装置EDDS及腹腔区域灌注ACDD化疗在进展期胃癌术后抗复发中的疗效.方法 2000年6月～2004年8月对86例进展期胃癌术后患者经由EDDS及ACDD给入化疗药物,观察术后复发情况.结果 86例患者经治疗至今已有56例过二年无瘤生存期(其中21例已过三年,7例已过四年),除1例脑多发灶,2例肝单发小转移,2例Douglas窝转移性结节,2例腹主动脉旁肿大淋巴结,余均未发现转移和复发.结论该方法并发症少,副作用轻,近、中期效果满意,操作简便易行.是一种较理想的AGC术后抗复发附加疗法.Objective To study the effect of EDDS and ACDD. Methods 86 radical gastrectomy patients with AGC were studied after accepted EDDS and ACDD. Results 56 tumor-free survivals were lived pass two years, in these cases, 7 pass four-year-living and 21 pass three-year-living. In all the 86 cases, just 8 cases were found recurrence condition. Conclusion EDDS and ACDD is a simple, safe and a feasible effective optimal clinical choice for the radical gastrectomy patients with AGC.

关 键 词：进展期胃癌 术后化疗 区域灌注 复发 

分 类 号：R735.2[医药卫生—肿瘤] R730.53[医药卫生—临床医学]