陕西省农村人群青光眼的流行病学调查  

Epidemiology of glaucoma in a rural population in Shaanxi Province

作　　者：任百超[1] 何媛[1] 陈莉[1] 杨建刚[1] 孙乃学[1] 

机构地区：[1]西安交通大学第二医院眼科,中国陕西省西安市710004

出　　处：《国际眼科杂志》2005年第5期1037-1042,共6页International Eye Science

基　　金：中国陕西省卫生厅资助项目(No.001225)

摘　　要：目的:调查陕西省农村≥50岁人群中青光眼的患病情况。方法:2003-07/12,采用按比例随机整群抽样的方法在陕南、陕北及关中3个地区农村调查8500人,其中≥50岁人群有2125人。所有受检人员均进行标准问卷调查,包括询问青光眼确诊史、家族史、发作史及手术史,并进行了相关的眼科检查,包括视力、外眼、前房深度及眼底检查。≥50岁人群应用压平式眼压计测量眼压,对可疑青光眼者进行进一步检查,包括复查眼压、前房角镜检查、激发试验、视野检查。结果:≥50岁人群中有1775人完成了青光眼的相关检查,受检率为83.53%。青光眼的患病率为2.14%,其中原发性闭角型青光眼、原发性开角型青光眼、继发性青光眼患病率分别为1.63%、0.39%、0.11%。55.26%青光眼患者存在不同程度的视力损伤,其中单眼低视力、双眼低视力、单眼盲及双眼盲所占比例依次为18.42%、5.26%、18.42%和13.16%。事前未被诊断为青光眼的患者占71.05%(27例),在另外28.95%(11例)有确诊史的青光眼患者中只有6例(54.55%)曾接受过治疗。正常眼的眼压平均值为13.9±2.2mmHg(1mmHg=0.133kPa),随着年龄的增加眼压有增加的趋势(P<0.05)。结论:陕西省农村人群青光眼的患病率为2.14%,但原发性闭角型青光眼和原发性开角型青光眼在原发性青光眼中的比例为4.18:1。无确诊史的青光眼患者占大多数。AIM： To assess the prevalence of glaucoma in a rural population 50 years old or older in Shaanxi Province, China. METHODS： By using a stratified, cluster-based and random sampling technique, 8 500 people were selected randomly from the north, the south and the middle regions of Shaanxi Province in Western China from July to December in 2003. Among them, 2 125 people were 50 years or older. All participants had an interview with a standard questionnaire and the questions included the previous diagnosis of glaucoma, family history and outbreak history. Then a detailed and relative eye examination was performed, including logarithm of the minimum angle of resolution visual acuity, external eye examination, deepness of the anterior chamber and the fundus examination. The intraocular pressure （IOP） of these people aged 50 years old or more was measured with Perkins applanation tonometry. A further examination was performed to those persons with suspicious glaucoma, including repeated tonometric examination, gonioscopy, provocative test, automated visual field testing, etc. RESULTS： There were 1 775 of the eligible 2 125 people of 50 years old or more were interviewed and examined from .luly to December, 2003. The response rate was 83.53%. The prevalence of glaucoma was 2.14%, and primary angle-closure glaucoma, primary angle-open glaucoma and secondary glaucoma accounted for 1.63%, 0.39% and 0.11% respectively. The visual function in 55.26% of glaucoma patients was damaged in certain degree, of which blindness at least in one eye as a result of glaucoma accounted for 31.58%. Of the 38 participants with glaucoma, 27 （71.05%） people had not been previously diagnosed or treated. Of the other 11 （28.95%） participants previously diagnosed, only 6 （54.55%） had been received treatment. The mean and standard deviation of i IOP among the right and left normal eyes was 13.9±2.2mmHg. With correlation analysis, IOP increased significantly with age increase after controlling for gender and blood pressure in

关 键 词：青光眼 患病率 视力损伤 眼压 原发性闭角型青光眼 农村人群 流行病学调查 陕西省 原发性开角型青光眼 青光眼患者 测量眼压 患病情况 随机整群抽样 

分 类 号：R775[医药卫生—眼科]