城区和煤矿区居民女性乳腺癌人群归因危险度的分析及比较  

Analysis of Population Attributable Risk of Breast Cancer in Urban and Mining Districts Inhabitants

作　　者：顾源[1] 何尚浦[1] 施侣元[1] 安莲珍 李国光[1] 朱康民 尹祖善 王兆旭 熊天寿[5] 

机构地区：[1]同济医科大学流行病学教研室,武汉430030 [2]平顶山矿务局卫生处 [3]襄樊市卫生防疫站 [4]老河口市卫生防疫站 [5]随州市卫生防疫站

出　　处：《中华流行病学杂志》1996年第2期102-104,共3页Chinese Journal of Epidemiology

摘　　要：为研究城区与煤矿区居民女性乳腺癌的危险因素,1986至1993年在湖北省武汉、襄樊、随州、老河口、荆沙等五城区,1991至1994年在河南省平顶山煤矿区先后开展了1:2配比的病例对照病因研究。多因素条件Logistic回归分析与人群归因危险度分析表明,城区居民乳腺癌主要的危险因素为乳腺良性病史、生育胎数少、初产年龄晚;相应的调整人群归因危险度(PARs)分别为0.3917、0.3564、0.1414;三因素综合人群归因危险度(PAR)为0.7419。煤矿区居民主要危险因素为乳腺良性病史、生育胎数少、月经紊乱、乳癌家族史;相应的PARs分别为0.1487、0.4781、0.1282、0.0791;综合PAR为0.6952。并对其公共卫生意义进行了探讨。In order to study the risk factors associated with female breast cancer, two 1:2 matched case-control studies were conducted from 1986 to 1993 in five cities in Hubei province and from1991 to 1994 in Pingdingshan coal mining districts in Henan province. The results of multivariate conditional logistic regression analysis showed that history of breast diseases, number of births, age of first birth were major risk factors for breast cancer in urban inhabitants. Their adjusted attributable risks (PARs)were 0.3917, 0.3564, 0.1414 respectively. The combined population attributable risks (PAR) for the three factors was 0.7419. History of breast diseases, number of births, menstrual disorder, family history of breast cancer were major risk factors in the Mining districts. Their PARs were 0.1487, 0.4781, 0.1282, 0.0791 respectively. PAR for four factors was 0.6952.

关 键 词：乳腺癌 LOGISTIC 回归模型 危险因素 发病率 

分 类 号：R737.9[医药卫生—肿瘤]