大剂量免疫球蛋白联合甲基强的松龙治疗格林-巴利综合征20例  

The analysis of high-dose human gamma globulin in combination in medron therapy for twenty children with acute Guillian-Barr'e syndrome

作　　者：李亚彬[1] 

机构地区：[1]安徽省阜阳市人民医院儿科,安徽阜阳236003

出　　处：《安徽医药》2005年第12期896-897,共2页Anhui Medical and Pharmaceutical Journal

摘　　要：目的观察大剂量免疫球蛋白(IVIG)联合甲基强的松龙(甲强龙)治疗格林-巴利综合征(GBS)的效果。方法对20例GBS患儿使用大剂量IVIG联合甲强龙治疗72 h后进行疗效评价。结果治疗前后患儿在四肢肌肉麻痹,颅神经麻痹(包括Ⅶ、Ⅸ、Ⅹ对颅神经),呼吸肌麻痹方面无明显变化(P>0.05)。结论大剂量IVIG联合甲强龙早期治疗GBS可有效抑制麻痹进展,尤其是呼吸肌麻痹进展,减少人工呼吸机通气应用,降低死亡率。Aim To observe therapy effect of high-dose human gamma globulin in combination in medron for children with acute Guillian-Barr＇e syndrome. Methods The paralysis results were evaluated in72h after high-dose human gamma globulin in combination in medron therapy for twenty children with acute Guillian-Barr＇e syndrome in recent years. Results The paralysis in four limbs,cranial nerves （includingVⅡ ,ⅠX, Xpairs）and respiratory muscles did not change significantly befor, after therapy. Conclusions The early therapy of high-dose human gamma globulin in combination in medron for children with acute Guillian-Barr＇e syndrome can bring effect to control paralvsis proagress. particularly in resniratorv paralysis,reduce to use artificial respirator and lower death rate.

关 键 词：免疫球蛋白 甲基强的松龙 格林-巴利综合征 大剂量免疫球蛋白 治疗前后 联合 颅神经麻痹 呼吸肌麻痹 IVIG 肌肉麻痹 

分 类 号：R745.43[医药卫生—神经病学与精神病学]