痰热清在非小细胞肺癌后程放疗中的应用  

Application of Tanreqing injection in late course radiotherapy for non-small cell lung cancer

作　　者：李士猛 洪铁艳 李耀洲[1] 俞亚琴 金宝翠[1] 

机构地区：[1]江苏省南通市瑞慈跃院肿瘤中心,江苏南通266006

出　　处：《世界肿瘤杂志》2005年第3期210-211,共2页Tumour Journal of the World

摘　　要：目的 研究痰热清在非小细胞肺癌后程放疗中的应用价值。方法 放疗：肺癌后程放疗，先常规分割照射40GY后缩野加量，总量64GY。用药：于后程缩野时给予药物治疗。结果 用药组与对照组急性放射性肺炎发生率分别为33.3％和15．2％（x^2=4．433，P=0．035），其组间差别有显著统计学意义。两组治疗后1月其急性放射性肺炎发生率下降为15．2％（x^2=4．201，P=0．04），其差别亦有显著统计学意义。在减轻放射性肺纤维化等晚反应方面两组相似。结论 在肺癌后程治疗中，应用痰热清能减轻放疗急性反应并缩短反应持续时间，对放射性肺纤维化等晚反应无价值。Objective To evaluate the significance of Tanreqing injection application on non-small cell lung cancer in late course radiotherapy. Methods Of 65 patients with lung cancer, 33 were subjected to receive Tanreqing injection（Group A）, and 32 were given conventional treatment（Group B）. Results The incidence of acute radioactive pneumonia were 33.3% in Group A and 15.2% in Group B, respectively, There was a statistical difference between two groups （x^2=4.433, P=0.035）. The acute radioactive pneumonia treated 1-month later were 15.2% in Group A and 37.5% in Group B, there was significant difference （x^2=4.201, P=0.040）. The conditions for both groups were similar in late reaction such as radioactive pulmonary fibrosis. Conclusion During late course radiotherapy, the application of Tanreqing injection could relieve acute reaction to radiotherapy and shorten the duration of the reaction. The late reactions, such as radioactive pulmonary fibrosis, are not affected.

关 键 词：痰热清 肺癌 后程放疗 放疗反应 

分 类 号：R734.2[医药卫生—肿瘤] R730.53[医药卫生—临床医学]