海洛因依赖伴发意识障碍与苯二氮滥用关系  

Observation on the Relationship between Consciousness Obstacle of Heroin Addicts and BZD Abuse

作　　者：陈良[1] 李身录[2] 郑威[1] 王久树[1] 

机构地区：[1]宁波市公安局强制戒毒所,宁波315500 [2]杭州市公安局安康医院,杭州311113

出　　处：《中国药物滥用防治杂志》2005年第5期265-266,共2页Chinese Journal of Drug Abuse Prevention and Treatment

摘　　要：目的:了解海洛因依赖者脱毒时伴发意识障碍与苯二氮类物质(BZD)滥用和伍用精神药物的关系。方法:对2002―2004年1470例戒毒病人中122例伴发意识障碍者进行回顾性分析。结果:本组意识障碍发生率为8.30%(122/1470例),其中有BZD滥用史的占78.69%(96/122例),脱毒时伍用精神药物的占77.08%(74/96例),说明有BZD滥用史和伍用精神药物有较高的意识障碍发生率。结论:海洛因依赖、BZD滥用、伍用精神药物三者可能存在某种互动关系。伍用药物使大脑皮层产生不完全抑制导致皮层下中枢机能释放。Objective： To study the relationship between consciousness obstacle of heroin addicts during detoxification and BZD abuse or combinational use of antipsychotic. Methods： To give 122 cases having consciousness obstacle retrospective analysis from 1470 heroin dependence cases treated in our hospital （2001-2004）. Results： Among 122 cases （8.30%） having consciousness obstacle, 96 cases （78.69%） had BZD abuse meantime; and among 96 cases having BZD abuse, 74 cases （77.08%） had combinational use of antipsychotic meantime. It means that in heroin addicts during detoxification, BZD abuse and combinational use of antipsychotic were accomplished with higher incidence of consciousness obstacle. Conclusion： There may be some interconversional relation between heroin dependence, BZD abuse or combinational use of antipsychotic. Combinational use of antipsychotic might make brain cortex incomplete restrain, which results in the release of subcortical center.

关 键 词：海洛因依赖 意识障碍 苯二氮[艹卓]滥用 海洛因依赖者 苯二氮 伴发 精神药物 回顾性分析 BZD 中枢机能 

分 类 号：R749.61[医药卫生—神经病学与精神病学]