生产环境紫露草微核原位监测与接触工人生物监测的对比研究  

A comparative study of the values between tradescantia micronucleus (Trad-MCN)in situ monitoring and biological monitoringamong exposed workers in workplaces.

作　　者：黎巧夫[1] 李来玉 叶华清 郑巧玲 陈润涛 

机构地区：[1]广东医学院第三附属医院,广东省劳动卫生职业病防治研究所

出　　处：《职业医学》1996年第1期11-12,共2页China Occupational Medicine

摘　　要：本文对石油化工企业的炼油污水处理和氧化沥青生产车间进行紫露草微核原位监测和车间空气的总烃、硫化氢、酚和氨浓度测定；同时检测接触工人的外周血淋巴细胞微核、双核细胞微核、ＳＣＥ和梁色体畸变。结果：紫露草微核原位监测与空气中毒物测定结果相关，即诱变剂测定超标的呈阳性。工人遗传毒性指标与紫露草微核原位监测也密切相关，即紫露草微核原位监测阳性的人遗传毒性指标也阳性。说明紫露草微核原位监测有一定的敏感性和特异性，它可起“第一级报警系统”的作用。he workplaces in petrochemical plant such asthe disposal of refinery sewage,the production ofoxydized asphalt and the synthesis of urea,were moni-tored by using Trad-MCN in situ monitoring tech-nique,Meanwhile the concentrations of hydrocarbon,hydrogen sulphide,phenol and ammonia were respec-tively measured.The incidences of micronucleus,SCE and chromosome aberration in the peripherallymphocytes of the exposed workers were also determined.It was found that there was a significant corre-lation between the results of Trad- MCN monitoringand the concentrations of pernicious agents in the oc-cupational environment.Trad-MCN test becamepositive in the workplaces where mutagens were be-yond the limited levels.The genotoxicological indicesin the workers were also closely correlated with theresults of Trad-MCN in situ monitoring.More posi-tive rates would occur in those workers working in thesite where the Trad-MCN test showed positive re-sults.It suggested that the Trad-MCN in situ moni-toring technique would be rather sensitive and speci-fic. It might serve as a“first alarming system”for oc-cupational environment monitoring.

关 键 词：紫露草微核 原位监测 微核 染色体畸变 

分 类 号：R115[医药卫生—公共卫生与预防医学]