睾丸内胚窦瘤(附6例报告)  

Endodermal Sinus Tumor of Testis(Report of Six Cases)

作　　者：鲁力[1] 马建辉[1] 李长岭[1] 

机构地区：[1]中国协和医科大学中国医学科学院肿瘤医院泌尿外科,北京100021

出　　处：《中国医刊》2005年第10期36-38,共3页Chinese Journal of Medicine

摘　　要：目的提高睾丸内胚窦瘤的诊治水平。方法对收治6例睾丸内胚窦瘤患者的诊治资料进行分析。6例均行患侧睾丸高位切除术;Ⅰ期3例,Ⅱ期2例,其中1例行腹膜后淋巴结清扫术(RPLND),Ⅲ期1例;术后在本院辅以化疗或放疗。结果1例失随访,其余5例随访2年5个月至10年,无局部复发及远处转移。结论睾丸高位切除术加术后化疗、放疗能明显提高睾丸内胚窦瘤的治愈率,对Ⅰ期患者辅以术后化疗,不必常规行RPLND,对Ⅱ期患者行RPLND加化疗或放疗的综合治疗,对Ⅲ期患者以化疗为主。Objective To improve the diagnosis and outcome of Endodermal sinus tumor of testis. Methods 6 cases of Endodermal sinus tumor of testis were reviewed in our hospital. All patients received an high inguinal orchiectomy as their initial treatment. Three patients with stage Ⅰ disease, two patients with stage Ⅱdisease and one patient with stage Ⅲ disease were treated with combination chemotherapy or radiotherapy following high inguinal orchiectomy. Only retroperitoneal lymph node dissection（RPLND） was performed in 1 case with stage Ⅱ disease. Results Follow -up for 2 years and 5 months to 10 years, no local recurrence and distant metastasis were found in these 6 cases. Conclusions Combined therapy, including high inguinal orchiectomy, chemotherapy and radiotherapy, can improve the cure rate of Endodermal sinus tumor of testis significantly. Post - operation chemotherapy is necessary for patients of stage Ⅰ , and RPLND is not necessary. Retroperitoneal lymph node dissection and post - operation chemotherapy or radiotherapy is necessary for patients of stage Ⅱ. Chemotherapy is of primal importance for patients of stage Ⅲ.

关 键 词：睾丸内胚窦瘤 诊断 治疗 

分 类 号：R737.2[医药卫生—肿瘤]