痛痹颗粒抗衰老实验研究  

Anti-aging empirical study of Tongbi Keli

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作  者:朱萱萱[1] 纪伟[1] 董朝蓝[1] 邱召娟[1] 张忠华[1] 

机构地区:[1]江苏省中医院,江苏南京210029

出  处:《现代中西医结合杂志》2005年第23期3062-3063,共2页Modern Journal of Integrated Traditional Chinese and Western Medicine

摘  要:目的观察痛痹颗粒抗衰老作用。方法采用16月龄SD大鼠,连续给予痛痹颗粒45 d,末次给药后取血分离测SOD、MDA,取胸腺、脾、肾上腺计算脏器系数。结果老龄组大鼠SOD明显降低,而MDA升高,痛痹颗粒经连续给药可明显升高SOD活力,降低MDA含量,对脏器系数未见有明显影响。结论痛痹颗粒可明显减少过氧化脂质过程,具有抗衰老作用。Objective It is to observe the anti-aging effect of Tongbi Keli. Methods The SD rats of 16 months were given Tongbi Keli continuously for 45 days. After the last medication, the blood was took out and separated to measure SOD and MDA, and the thymus gland, spleen and adrenal gland were took out and computed the organ coefficient. Results SOD in aging group debased obviously and MDA heightened. Through consecutive medication, Tongbi Keli could obviously increase SOD activity and debase MDA content, but had not obvious influence on organ coefficient. Conclusion Tongbi Keli can obviously lessen the peroxidized course of lipoids and it has anti-aging action.

关 键 词:痛痹颗粒 药效 SOD MDA 

分 类 号:R-332[医药卫生]

 

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