工作场所空气中乙醛测定方法的规范化研究  

Study on Validation of Acetaldehyde Determination in the Air of Workplaces

作　　者：张志虎[1] 邵华[1] 张梦萍[1] 冯斌[1] 

机构地区：[1]山东省职业卫生与职业病防治研究院,山东济南250062

出　　处：《工业卫生与职业病》2005年第6期361-363,共3页Industrial Health and Occupational Diseases

基　　金：国家自然科学基金(30471429);山东省自然科学基金资助(Y2002C30)

摘　　要：目的建立一种实用的工作场所空气中乙醛的采样及测定方法.方法用浸渍2,4-二硝基苯肼(DNPH)的硅胶管采集空气样品,用乙腈在超声中洗脱,高效液相色谱分离,二极管阵列检测器检测.结果方法简便、准确、灵敏度高.标准曲线的相关系数为0.999 5,加标回收率为97.16%～104.63%,相对标准偏差为0.08%～0.29%,平均采样效率为99.84%.结论本方法各项指标均达到<工作场所空气中毒物检测方法的研制规范>的要求,能准确地测定空气中乙醛含量.Objective To establish a practical method for sampling and determining acetaldehyde in the air of workplaces. Methods Glass tubes filled with DNPH-coated silica gel were used for air sampling. The DNPH-derivatives were extracted from the silica gel by ultrasonic treatment with acetonitrile. Analysis of DNPH-derivatives was carried out using HPLC with diode array （UV/DAD） detection. Results The method was simple, accurate, and highly sensitive. The correlation coefficient of calibration curves was 0. 999 5. Recovery rates of 97.16%-104.63% were determined. The relative standard 0.08%-0.29% and average sampling efficiency 99.84% were obtained. Conclusions This method is conformed to the requirements of ＂Standardization of Methods for Determination of Toxic Substance in Workplace＂, by which acetaldehyde in air could be determined accurately.

关 键 词：乙醛 检测 高效液相色谱法 工作场所 

分 类 号：R134.4[医药卫生—劳动卫生]