隆突性皮肤纤维肉瘤36例临床病理分析  

Clinico Pathological Analysis of 36 Cases of Dermatofibrosarcoma Protuberans

作　　者：黄经光[1] 符青云[1] 

机构地区：[1]暨南大学医学院第六附属医院病理科,广东江门529031

出　　处：《中国误诊学杂志》2005年第14期2612-2614,共3页Chinese Journal of Misdiagnostics

摘　　要：目的:提高对隆突性皮肤纤维肉瘤(DFSP)组织变异的认识。方法:对36例DFSP临床病理资料总结分析及随访,其中13例加做免疫组化标记。结果:36例DFSP的组织形态均有经典的车辐状或席纹状结构,其中6例伴有纤维肉瘤区域、3例伴有黏液样区域、2例瘤细胞含有黑色素、1例可见肌样结节和肌样束。作免疫标记的13例DFSP瘤细胞CD34、VIM均阳性。结论:掌握DFSP各亚型组织形态变异的特点,并辅以CD34标记,有助DFSP的诊断及鉴别诊断。Objective：To improve the recongnition of histological variants of dermatofibrosarcoma protuberans （DFSP）. Methods：Thirty-six cases of DFSP were followed up and the clinical pathological datas were analyzed. Among them, 13 cases were performed with immunohistochemlcal staining. Results： Microscopically, All 36 cases had typical storiform structure ,of which,fibrosarcoma areas were found in 6 cases,myxoid areas in 3 cases, pigments in the tumours in 2 cases and desmoid area in 1 case. CD34 and Vimentin were all positive in 13 cases which were performed immunohistochemical staining. Conclusions ：It is very useful to diagnose DFSP by grasping the characteristic histoligical variants of DFSP and the marker of CD34 by immunohistochemical staining.

关 键 词：皮肤纤维肉瘤/病理学 皮肤肿瘤/病理学 免疫组织化学 

分 类 号：R739.502.1[医药卫生—肿瘤]