宫颈癌临床预后的影响因素分析  

The Factors Influencing of Clinical Prognosis of Cervical Carcinoma

作　　者：万恂恂[1] 刘筱娴[2] 沈敏[2] 

机构地区：[1]湖南师范大学医学院,长沙410006 [2]华中科技大学同济医学院,武汉430030

出　　处：《医学与社会》2005年第11期26-27,共2页Medicine and Society

基　　金：湖南省教育厅资助课题(03C246);湖南省卫生厅资助课题(B2003-098)

摘　　要：目的探讨宫颈癌病理特征和治疗方案与宫颈癌临床预后的相关性,为宫颈癌临床治疗提供科学参考。方法1158例宫颈癌住院患者作为研究对象,对宫颈癌预后进行单因素分析和多因素多项有序反应变量Logistic逐步回归分析,所有分析采用SAS8.0专业统计软件完成。结果单因素分析有临床分期、分化程度、癌灶体积、周围组织器官浸润、淋巴结转移、远处转移、并发症和治疗方案等8个因素与宫颈癌的临床预后相关。Logistic逐步回归分析结果显示:临床分期、医院感染、单纯手术、有并发症和淋巴结转移是宫颈癌临床转归的危险因素。结论宫颈癌的临床分期、并发症和淋巴结转换与临床预后的关系密切;宫颈癌的治疗以综合治疗方式更为有效。Objective This study was designed to explore pathological features and therapeutic method in relation to clinical prognosis of cervical carcinoma and to provide scientific references for making effective method of treatment. Methods A sample of 1158 hospitalized patients with a complete case report was used as the study observations. Some related factors to therapeutic resuhs of cervical cancer were analyzed singly, and then were analyzed with a multi-ordinal-categories Logistic regression model. All data were analyzed with statistic soft ware of SAS8. 0 on a computer. Resutls The reuhs of single factor analysis indicated that there were 8 realated factors to clinical prognosis. Logistic regression model showed that there were only five influence-factors of prognosis, including clinical stages, hospital infection, simple surgery, complications and lymphoglandulae transference. Conclusion The study indicates that there is a strong relationship between some pathological features and clinical prognosis of cervical carcinoma and thai the comprehensive therapy is more effective.

关 键 词：宫颈癌 病理特征 治疗方案 临床预后 LOGISTIC回归 

分 类 号：R-05[医药卫生]