内窥镜手术治疗鼻腔-鼻窦恶性肿瘤:病例报告及文献复习  

Endoscopic surgery for sinonasal malignant neoplasms: case report and literature review

作　　者：范献良[1] 剪京芬[1] 郑国玲[2] 

机构地区：[1]山东大学第二医院耳鼻咽喉科,山东济南250033 [2]山东大学西校区医院

出　　处：《山东大学耳鼻喉眼学报》2005年第5期305-307,F0003,共4页Journal of Otolaryngology and Ophthalmology of Shandong University

摘　　要：目的:探讨内窥镜手术切除鼻腔及鼻窦恶性肿瘤的适应证、可行性及治疗效果。方法:鼻内窥镜下切除鼻腔-鼻窦恶性肿瘤4例,其中低分化鳞癌1例、黏液表皮样癌1例、非霍奇金淋巴瘤(T细胞型)1例、乳头状瘤恶变1例。其中2例行术后放疗,1例行术后化疗,1例未行放疗及化疗。结果:术后随访2．5-7年,平均4．3年,患者均健在。其中1例生存5年,因术后3年局部复发,再次行内窥镜手术。结论:经选择的鼻腔及鼻窦早期原发性或复发性恶性肿瘤,可经内窥镜手术彻底切除,术后配合放疗或化疗,可取得满意的治疗效果,其优点是损伤小、恢复快、无面部瘢痕,易被患者接受。Objective： To explore the indication, feasibility and therapeutic efficiency of endoscopic surgery for resection of sinonasal malignant tumors. Methods： Resections were performed by endoscopic surgeries on 4 cases, including 1 of low differentiated squamous cell carcinoma, 1 of mucoepidermoid carcinoma, 1 of non - Hopkins lymphoma and 1 case of carcinoma transformed from inverted papilloma. Two cases were treated by radiotherapy, 1 by chemotherapy, and 1 by neither radiotherapy nor chemotherapy postoperatively. Results： During a follow - up of 2.5 - 7 years, 3 patients were alive free of tumour but one was reoperated on by endoscopy due to local recurrence 3 years after the first surgery. Conclusions： Early stage primary or secondary sinonasal malignant neoplasm can be removed completely by endoscopic surgery. Satisfactory results can be achieved by combination with radiotherapy or chemotherapy after operation. This method is characterized by mini - invasion, soon recovery, and no disfigurement .

关 键 词：内窥镜检查 鼻腔 鼻窦 肿瘤 

分 类 号：R739.62[医药卫生—肿瘤]