Preliminary Application of Perfusion Imaging in Neoplasm in the Brain and Body with Multi-slice Helical CT  

多层螺旋CT灌注成像在脑肿瘤的初步应用(英文)

作　　者：李智勇[1] 伍建林[1] 宁殿秀[1] 王克礼[1] 韩睿[1] 刘晓风[1] 郎志谨[1] 

机构地区：[1]大连医科大学附属第一医院放射科,1116011

出　　处：《The Chinese-German Journal of Clinical Oncology》2005年第5期317-320,327-328,共6页中德临床肿瘤学杂志（英文版）

摘　　要：Objective： To evaluate the clinical value of perfusion imaging in neoplasm in the brain and body with Multi-slice helical CT. Methods： Twenty-eight patients with neoplasm were subjected to perfusion imaging with multi-slice helical CT, including 22 patients with brain neoplasm and 6 patients with body neoplasm. At first, CT routine scan was preformed to localize central slices of neoplasm. Then perfusion imaging of 4 and identical slices in central slices of neoplasm was performed by using CT cine scan. Scanning images were transferred into ADW3.1 work-station to create and analyze perfusion images and parameters. Results： Perfusion parameters of cerebral neoplasm had a remarkable increase. But, CBF value of different cerebral neoplasms had partial overlap; CBV value was increased slightly; MTT value had no apparently clinical value; PS value was increased significantly, pituitary neoplasm〉meningoma〉cerebral glioma≈cerebral metastasis. PS value could reveal the characters of cerebral neoplasm and had apparently clinical value. Perfusion parameters of body neoplasms have a remarkable increase too. Body tumors were liable to be interfered by breath movement. Perfusion parameters were helpful to differentiation diagnosis of neoplasm in the brain and body. PS images of neoplasm in the brain and body were helpful to defining tumor outline and finding small tumor. Conclusion： MSCT perfusion imaging provided a precise and relative simple method to quantitatively estimate blood perfusion status in tumors in the brain and body. The technique can be easily implemented on clinical scanners.

关 键 词：tomography  X-ray computed NEOPLASM HEMODYNAMICS 

分 类 号：R739.4[医药卫生—肿瘤] R730.44[医药卫生—临床医学]