DSA介入治疗晚期肿瘤病人效果观察  

Observation on effects of DSA transcatheter arterial chemoembolization therapy for patients with advanced cancer

作　　者：郑军[1] 王济明[1] 张隆群[1] 

机构地区：[1]重庆医科大学附属第一医院肝胆外科,重庆400016

出　　处：《重庆医科大学学报》2005年第5期751-752,共2页Journal of Chongqing Medical University

摘　　要：目的:分析2003年6月至2004年12月所做35例在DSA下经导管动脉内化疗栓塞(transcatheter arterial chemoem-bolization,TACE)治疗的肿瘤患者的结果,包括肝癌21肝癌病人中19用EPI+HCPT+5-FU+新福菌素等多种不同化疗药物联合应用。结果:本组21例肝癌病人中19例症状明显缓解(90%),3例无明显疗效;6例结、直肠癌术后病人经灌注化疗后,未出现明显化疗副反应,无复发征象;6例胃癌病人中2例印戒细胞癌患者死亡,其余4例腺癌病人继续随访,2例胰头癌经术后介入治疗,无复发及转移征象。结论:对不能手术的肿瘤病人采用介入化疗可以抑制肿瘤的生长,延长生存时间;对手术后的病人辅以介入治疗,即可提高疗效,又可明显减少化疗药物的副反应,因此通过DSA介入灌注化疗值得临床推广。Objective ：To evaluate 35 eases of cancer by transcatherter arterial chemoembolization （TACE）during June, 2003 and December. 2004 in the department where the authers worked among which 21 cases were liver cancer, 6 gastric cancer, 6 colon cancer and rectum cancer, and 2 cancer of head of pancreas. Methods ：Seldinger＇s method was used in DSA and combined with EPI .HCPT. 5 - FU and aetinomycin D. Results ：The overall responsive rate was 90 % （19/12） in hepatic carcinoma patients and progressive disease appeared （PD） in three patients, no evident side - effects of chemotherapy appeared and no recurrence occured in 6 eases of colon cancer and rectum cancer. 2 patients （signet- ring cell carcinoma） died in 6 cases of stomach cancer and the other 4 cases were followed up ,2 cases of carcinoma of head of pancreas also no recurrence and no metastasis after treated by TACE. Conclusion ： The method of TACE in DSA for patients who had no chance to be operated has the effect of inhibiting the growth of carcinoma cells and prolong patient＇s living time. For pastaperative patients TACE can also decrease the side-effects of chemotherapy and increase the drug effectivenes.s, .so this method is very valuable in clinic popularization.

关 键 词：肿瘤 介入治疗 经导管动脉内化疗栓塞 灌注化疗 

分 类 号：R730.5[医药卫生—肿瘤]