纵隔和大脑髓样肉瘤1例报告并文献复习  

Myeloid Sarcoma of Mediastinum and the Brain-one Case Report and Review of Literature

作　　者：张克俭[1] 谭细友[1] 鲁植艳[1] 郭广松[1] 龚铃玲[1] 

机构地区：[1]武汉大学中南医院,武汉430071

出　　处：《武汉大学学报（医学版）》2005年第6期785-787,共3页Medical Journal of Wuhan University

摘　　要：目的:提高对髓样肉瘤(MS)的认识。方法:报道1例相继发生纵隔和大脑髓样肉瘤的诊断及治疗经过,并进行文献复习。结果:经标准DA方案化疗及局部放疗,髓样肉瘤达完全缓解。结论:髓样肉瘤在石蜡切片上因其形态学与非霍杰金淋巴瘤极其相似而容易造成误诊,免疫组化并结合血和骨髓常规可提高诊断率。联合化疗和局部放疗,有望改善不良预后。Objective： To enhance understanding to myeloid sarcoma. Methods： A case myeloid sarcoma of mediastinum and the brain sequentially with review of literatures was reported. Results： The present patient was treated with standard daunorubicin and cytarabine induction chemotherapy and involved field radiotherapy. He was in complete remission. Conclusion： Myeloid sarcomas are difficult to identify in routine paraffin-embedded tissue sections and usually misdiagnosed as nonHodgkin lymphomas because they may resemble lymphoma morphologically. Immunohistochemistry study and combination with blood and bone marrow routine are helpful to its diagnosis. Chemotherapy and involved field radiotherapy are beneficial and may improve poor prognosis.

关 键 词：肉瘤 髓样 纵隔 大脑 免疫组化 联合化疗 

分 类 号：R733.71[医药卫生—肿瘤]