卵巢癌靶向治疗研究进展  

The Studies on Targeted Therapy of Ovarian Cancer

作　　者：郝权[1] 田菁[1] 王耕辛[1] 

机构地区：[1]天津医科大学附属肿瘤医院盆腔肿瘤科,天津市300060

出　　处：《中国肿瘤临床》2005年第22期1315-1318,共4页Chinese Journal of Clinical Oncology

摘　　要：靶向治疗作为一种新的肿瘤治疗手段,能够提高药物对肿瘤细胞的杀伤力,而同时减少对正常组织器官的不良作用,已逐步应用于临床治疗,且在卵巢癌的治疗中较传统治疗方式显示出明显优势。本文分别从单克隆抗体、酪氨酸激酶、肿瘤血管生成、基因治疗、光动力学治疗五个侧面对靶向治疗在卵巢癌治的研究现况、治疗应用及前景进行了总结及瞻望。Targeted therapy, a promising treatment, offering the hope of improving the medical management of ovarian cancer while being less toxic to normal cells, has been applied in clinical trials gradually and has demonstrated significant benefit compared with traditional therapies. This review investigates the research, application and prospect of targeted therapy in five aspects such as monoclonal antibody, tyrosinase kinase inhititors, anti-angiogenic agents, gene therapy and photodynamics therapy, in an attempt to understand the mechanism and the curative effect better.

关 键 词：卵巢癌 靶向治疗 单克隆抗体 基因治疗 酪氨酸激酶抑制剂 

分 类 号：R737.31[医药卫生—肿瘤]